iPTMnet Report for P19440 (GGT1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P19440 / GGT1_HUMAN
Protein Name Glutathione hydrolase 1 proenzyme precursor
Gene Name Name: GGT1
Synonyms:GGT;
Organism Homo sapiens (Human)

PRO ID PR:P19440
DAG View
PRO Name glutathione hydrolase 1 proenzyme (human)
Definition A glutathione hydrolase 1 proenzyme that is encoded in the genome of human.
Short Label hGGT1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P19440 (GGT1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N95 N-Glycosylation GlyGen   UniProt 24047895, 26013825, 20622017
N120 N-Glycosylation GlyGen   UniProt 26013825, 20622017, 19159218, ...24190977, 29391424, 19349973, 24047895, 17924658, 29741879
K172 Ubiquitination PhosphoSitePlus
K181 Ubiquitination PhosphoSitePlus
N230 N-Glycosylation GlyGen   UniProt 24047895, 26013825, 20622017, ...19159218
N266 N-Glycosylation GlyGen   UniProt 17924658, 24047895, 26013825, ...20622017
N297 N-Glycosylation GlyGen   UniProt 29741879, 20622017, 29391424
K334 Ubiquitination PhosphoSitePlus
N344 N-Glycosylation GlyGen   UniProt 26013825, 20622017, 29391424, ...29741879, 17924658, 24047895
N511 N-Glycosylation GlyGen   UniProt 26013825, 20622017, 32125861, ...19159218, 24190977, 23090970, 29391424, 15084671, 24047895, 17924658, 29741879
T550 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K334 R334 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T550 M550 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]