iPTMnet Report for P18887 (XRCC1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P18887 / XRCC1_HUMAN
Protein Name DNA repair protein XRCC1
Gene Name Name: XRCC1
Organism Homo sapiens (Human)

PRO ID PR:P18887
DAG View
PRO Name DNA repair protein XRCC1 (human)
Definition A DNA repair protein XRCC1 that is encoded in the genome of human.
Short Label hXRCC1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P18887 (XRCC1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K129 Ubiquitination PhosphoSitePlus
K138 Ubiquitination PhosphoSitePlus
S140 Phosphorylation HPRD   PhosphoSitePlus   UniProt 20068231
S151 Phosphorylation PhosphoSitePlus
S162 Phosphorylation PhosphoSitePlus
K169 Acetylation PhosphoSitePlus
K169 Ubiquitination PhosphoSitePlus
K176 Sumoylation PhosphoSitePlus
S184 Phosphorylation O96017 (CHEK2) PhosphoSitePlus 18971944
T198 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332, 20068231
S199 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18669648, 19690332, 20068231
T202 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
S204 Phosphorylation HPRD   PhosphoSitePlus   UniProt 20068231
S210 Phosphorylation O96017 (CHEK2) PhosphoSitePlus 18971944
Y211 Phosphorylation HPRD   PhosphoSitePlus 20068231
S224 Phosphorylation HPRD   phospho.ELM 18669648
S226 Phosphorylation P24941 (CDK2) HPRD   phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18847512, 18669648, ...19690332, 20068231
S229 Phosphorylation P24941 (CDK2) HPRD   phospho.ELM   PhosphoSitePlus 18669648, 18847512, 20068231
S234 Phosphorylation PhosphoSitePlus
T235 Phosphorylation PhosphoSitePlus
S236 Phosphorylation HPRD   PhosphoSitePlus 19664995, 20068231
S241 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 18212344, ...19007248, 19664995, 19651622, 18669648, 19690332, 20068231
K247 Sumoylation PhosphoSitePlus
K256 Acetylation PhosphoSitePlus
K256 Sumoylation PhosphoSitePlus
T257 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
S259 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
K260 Acetylation PhosphoSitePlus
S266 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 17287340, 17081983, 19651622, ...18669648, 23186163, 20068231
S268 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 19651622, 17081983, 20068231
K271 Acetylation PhosphoSitePlus
T279 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
T281 Phosphorylation PhosphoSitePlus   UniProt 23186163
T284 Phosphorylation O96017 (CHEK2) IntAct   PhosphoSitePlus   RLIMS-P   Signor 18971944
T296 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T296 Phosphorylation PhosphoSitePlus
K298 Acetylation PhosphoSitePlus
R310 Methylation PhosphoSitePlus
K341 Ubiquitination PhosphoSitePlus
K348 Ubiquitination PhosphoSitePlus
S357 Phosphorylation PhosphoSitePlus   RLIMS-P 28740101
T358 Phosphorylation PhosphoSitePlus   RLIMS-P 28740101
T367 Phosphorylation PhosphoSitePlus   RLIMS-P 28740101
Y370 Phosphorylation PhosphoSitePlus
S371 Phosphorylation P78527 (PRKDC) neXtProt   PhosphoSitePlus   RLIMS-P   UniProt 16397295
K383 Ubiquitination PhosphoSitePlus
S408 Phosphorylation P68400 (CSNK2A1) HPRD   phospho.ELM   PhosphoSitePlus   UniProt 17081983, 25477519, 19651622, ...18669648, 20068231
S409 Phosphorylation P68400 (CSNK2A1) HPRD   phospho.ELM   PhosphoSitePlus   UniProt 17081983, 25477519, 19651622, ...18669648, 20068231
S410 Phosphorylation P68400 (CSNK2A1) HPRD   phospho.ELM   PhosphoSitePlus   UniProt 17081983, 25477519, 19651622, ...18669648, 20068231
S416 Phosphorylation P68400 (CSNK2A1) HPRD   phospho.ELM   PhosphoSitePlus 17081983, 25477519, 19651622, ...18669648, 20068231
S418 Phosphorylation P68400 (CSNK2A1) HPRD   phospho.ELM   PhosphoSitePlus 19651622, 18669648, 25477519, ...17081983
S421 Phosphorylation P68400 (CSNK2A1) HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 25477519, 17081983, ...20068231
K431 Acetylation PhosphoSitePlus
K431 Ubiquitination PhosphoSitePlus
T437 Phosphorylation PhosphoSitePlus
T440 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
T440 Phosphorylation HPRD   PhosphoSitePlus 19664995
S446 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
S446 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 17081983, 19664995, ...18669648, 24275569
S447 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
S447 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 17287340, 17081983, ...19664995, 18452278, 19651622, 18669648, 24275569, 23186163
T453 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
T453 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 21406692, 17287340, ...17081983, 19664995, 18452278, 19651622, 18669648, 24275569, 20166139, 23186163, 19690332
T457 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19413330, 21406692, 23186163, ...18452278, 19651622, 24275569, 20166139
S461 Phosphorylation P68400 (CSNK2A1) HPRD   PhosphoSitePlus   UniProt 15066279, 19690332, 24275569, ...18452278
S475 Phosphorylation P68400 (CSNK2A1) HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P 15367657, 33907233, 18452278, ...25477519, 15066279
S485 Phosphorylation P68400 (CSNK2A1) , P19784 (CSNK2A2) HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 15367657, 20471329, 33907233, ...18452278, 25477519, 15066279, 30316146, 19690332
T488 Phosphorylation P19784 (CSNK2A2) , P68400 (CSNK2A1) HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 15367657, 20471329, 33907233, ...18452278, 25477519, 15066279, 30316146, 19690332
Y515 Phosphorylation P68400 (CSNK2A1) HPRD   PhosphoSitePlus 25477519, 18452278
S518 Phosphorylation P68400 (CSNK2A1) , P19784 (CSNK2A2) HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 15367657, 29059378, 20471329, ...33907233, 18452278, 25477519, 19155274, 15066279, 30316146
T519 Phosphorylation P68400 (CSNK2A1) , P19784 (CSNK2A2) HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 15367657, 29059378, 20471329, ...18452278, 25477519, 15066279, 19155274, 30316146
T523 Phosphorylation P19784 (CSNK2A2) , P68400 (CSNK2A1) HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 15367657, 29059378, 20471329, ...26519825, 18452278, 25477519, 19155274, 15066279, 30316146
S525 Phosphorylation P68400 (CSNK2A1) phospho.ELM   PhosphoSitePlus   RLIMS-P 15066279, 25477519, 19155274, ...29059378
S578 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus 25477519
K620 Ubiquitination PhosphoSitePlus
Y627 Phosphorylation PhosphoSitePlus