iPTMnet Report for P18085 (ARF4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P18085 / ARF4_HUMAN
Protein Name ADP-ribosylation factor 4
Gene Name Name: ARF4
Synonyms:ARF2;
Organism Homo sapiens (Human)

PRO ID PR:P18085
DAG View
PRO Name ADP-ribosylation factor 4 (human)
Definition An ADP-ribosylation factor 4 that is encoded in the genome of human.
Short Label hARF4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P18085 (ARF4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation PRO
G2 Myristoylation UniProt 25255805
S6 O-Glycosylation GlyGen 33465208
S7 O-Glycosylation GlyGen 33465208
S10 O-Glycosylation GlyGen 35083852, 34019948, 34725712, ...35138101, 33465208
K15 Ubiquitination PhosphoSitePlus
K16 Ubiquitination PhosphoSitePlus
Y35 Phosphorylation PhosphoSitePlus
K36 Acetylation PhosphoSitePlus
K36 Ubiquitination PhosphoSitePlus
K38 Ubiquitination PhosphoSitePlus
Y58 Phosphorylation PhosphoSitePlus
Y81 Phosphorylation PhosphoSitePlus
K109 Ubiquitination PhosphoSitePlus
K127 Ubiquitination PhosphoSitePlus
S137 Phosphorylation PhosphoSitePlus
K142 Ubiquitination PhosphoSitePlus
S147 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 19664994
T152 Phosphorylation PhosphoSitePlus
Y167 Phosphorylation PhosphoSitePlus


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000036207 (hARF4/Ac:1) acM1 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K15 N15 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y35 N35 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y35 C35 Biomuta DOID:3571 / liver cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ]
S147 F147 Biomuta DOID:4159 / skin cancer [ cosmic ]