Protein Information

Cytoscape View


UniProt AC / UniProt ID P17947 / SPI1_HUMAN
Protein Name Transcription factor PU.1
Gene Name Name: SPI1
Organism Homo sapiens (Human)

PRO ID PR:P17947
DAG View
PRO Name transcription factor PU.1 (human)
Definition A transcription factor PU.1 that is encoded in the genome of human.
Short Label hSPI1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P17947 (SPI1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S17 Phosphorylation PhosphoSitePlus
S41 Phosphorylation PhosphoSitePlus   RLIMS-P 33188146
S140 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 33188146, 24275569
S146 Phosphorylation PhosphoSitePlus   UniProt 24275569
S253 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S146 Y146 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]