iPTMnet Report for P17066 (HSPA6)
Protein Information
| UniProt AC / UniProt ID | P17066 / HSP76_HUMAN |
| Protein Name | Heat shock 70 kDa protein 6 |
| Gene Name | Name: HSPA6 Synonyms:HSP70B'; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P17066 |
| PRO Name | heat shock 70 kDa protein 6 (human) |
| Definition | A heat shock 70 kDa protein 6 that is encoded in the genome of human. |
| Short Label | hHSPA6 |
| Category | organism-gene |
P17066 (HSPA6) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| T39 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T40 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S42 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y43 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T47 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T49 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R51 | Methylation | score1 | PhosphoSitePlus | |||
| K58 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S59 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K73 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K79 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K90 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K102 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K104 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K114 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S123 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K128 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K130 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K142 | Methylation | score1 | PhosphoSitePlus | |||
| K142 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K161 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y185 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T224 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 18452278 | ||
| T228 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K259 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T267 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S278 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S298 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T300 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S309 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S314 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T315 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K321 | Acetylation | score1 | PhosphoSitePlus | |||
| K321 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K327 | Acetylation | score1 | PhosphoSitePlus | |||
| K327 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K330 | Methylation | score1 | PhosphoSitePlus | |||
| K330 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K347 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K350 | Acetylation | score1 | PhosphoSitePlus | |||
| K350 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K359 | Acetylation | score1 | PhosphoSitePlus | |||
| K359 | Sumoylation | score1 | PhosphoSitePlus | |||
| K359 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K363 | Sumoylation | score1 | PhosphoSitePlus | |||
| K363 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S364 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y373 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K386 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S402 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T407 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K453 | Ubiquitination | score1 | PhosphoSitePlus | |||
| R460 | Methylation | score1 | PhosphoSitePlus | |||
| R471 | Methylation | score1 | PhosphoSitePlus | |||
| R495 | Methylation | score1 | PhosphoSitePlus | |||
| K499 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K502 | Acetylation | score1 | PhosphoSitePlus | |||
| K502 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T504 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K509 | Acetylation | score1 | PhosphoSitePlus | |||
| K509 | Sumoylation | score1 | PhosphoSitePlus | |||
| K509 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K514 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K528 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K541 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K552 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K563 | Methylation | score1 | PhosphoSitePlus | |||
| K563 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K598 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T40 | A40 | Biomuta | DOID:1319 / brain cancer [ cosmic ] | |
| T47 | A47 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| K73 | R73 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
| S123 | F123 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| K128 | N128 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
| T267 | K267 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
| S364 | N364 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| R460 | H460 | Biomuta | DOID:363 / uterine cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] | |
| R471 | H471 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic, icgc ] | |
| K528 | R528 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
| K528 | N528 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic ] | |
| K541 | N541 | Biomuta | DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ] |
DAG View