iPTMnet Report for P16662 (UGT2B7)
Protein Information
UniProt AC / UniProt ID | P16662 / UD2B7_HUMAN |
Protein Name | UDP-glucuronosyltransferase 2B7 precursor |
Gene Name | Name: UGT2B7 Synonyms:UGTB2B9; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P16662 |
PRO Name | UDP-glucuronosyltransferase 2B7 (human) |
Definition | A UDP-glucuronosyltransferase 2B7 that is encoded in the genome of human. |
Short Label | hUGT2B7 |
Category | organism-gene |
P16662 (UGT2B7) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
N68 | N-Glycosylation | score4 | GlyGen UniProt | 22240840, 19159218 | ||
Y236 | Phosphorylation | score1 | PhosphoSitePlus | |||
N315 | N-Glycosylation | score2 | GlyGen | 22240840 | ||
K430 | Acetylation | score1 | PhosphoSitePlus | |||
Y438 | Phosphorylation | score4 | PhosphoSitePlus Signor | 19289110, 21056984 | ||
Y438 | Phosphorylation | P12931 (SRC) | score4 | PhosphoSitePlus Signor | 19289110, 21056984 | |
R469 | Methylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K430 | N430 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
R469 | S469 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
R469 | H469 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] DOID:1319 / brain cancer [ icgc ] | |
R469 | C469 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:10283 / prostate cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic, icgc ] |