iPTMnet Report for P16520 (GNB3)
Protein Information
| UniProt AC / UniProt ID | P16520 / GBB3_HUMAN |
| Protein Name | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 |
| Gene Name | Name: GNB3 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P16520 |
| PRO Name | guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 (human) |
| Definition | A guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 that is encoded in the genome of human. |
| Short Label | hGNB3 |
| Category | organism-gene |
DAG ViewP16520 (GNB3) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| Y59 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S72 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S74 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K78 | Acetylation | score1 | PhosphoSitePlus | |||
| Y85 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T86 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T87 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S140 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T143 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y145 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K177 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S309 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C317 | Methylation | score1 | IEDB | 31844290 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S74 | A74 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S74 | * | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
| S74 | L74 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
| T87 | N87 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S140 | C140 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] |
