iPTMnet Report for P16389 (KCNA2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P16389 / KCNA2_HUMAN
Protein Name Potassium voltage-gated channel subfamily A member 2
Gene Name Name: KCNA2
Organism Homo sapiens (Human)

PRO ID PR:P16389
DAG View
PRO Name potassium voltage-gated channel subfamily A member 2 (human)
Definition A voltage-gated potassium channel subunit KCNA2 that is encoded in the genome of human.
Short Label hKCNA2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P16389 (KCNA2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K49 Ubiquitination PhosphoSitePlus
Y132 Phosphorylation phospho.ELM   PhosphoSitePlus 8261514
S308 Phosphorylation PhosphoSitePlus
Y415 Phosphorylation phospho.ELM   PhosphoSitePlus 12151401
Y417 Phosphorylation phospho.ELM   PhosphoSitePlus 12151401
S434 Phosphorylation RLIMS-P 18056633
S440 Phosphorylation PhosphoSitePlus   RLIMS-P 19389710, 18056633
S441 Phosphorylation PhosphoSitePlus   RLIMS-P 19389710, 18056633
S449 Phosphorylation neXtProt   RLIMS-P 19389710
S451 Phosphorylation PhosphoSitePlus
T452 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y132 Phosphorylation PRO 15215309
Y415 Phosphorylation HPRD 12151401
Y417 Phosphorylation HPRD 12151401
S440 Phosphorylation PRO 18056633
S441 Phosphorylation PRO 18056633


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000036584 (hKCNA2/iso:1/Phos:1) pY132 PRO 15215309
PR:000036587 (hKCNA2/iso:1/Phos:2) pS440,pS441 PRO 18056633


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S441 F441 Biomuta DOID:4159 / skin cancer [ cosmic ]
S449 G449 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]