iPTMnet Report for P14854 (COX6B1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P14854 / CX6B1_HUMAN
Protein Name Cytochrome c oxidase subunit 6B1
Gene Name Name: COX6B1
Synonyms:COX6B;
Organism Homo sapiens (Human)

PRO ID PR:P14854
DAG View
PRO Name cytochrome c oxidase subunit 6B1 (human)
Definition A cytochrome c oxidase subunit 6B1 that is encoded in the genome of human.
Short Label hCOX6B1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P14854 (COX6B1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378
K8 Sumoylation PhosphoSitePlus
K8 Ubiquitination PhosphoSitePlus
K13 Ubiquitination PhosphoSitePlus
C30 Methylation IEDB 31844290
Y34 Phosphorylation PhosphoSitePlus
C40 Methylation IEDB 31844290
K42 Ubiquitination PhosphoSitePlus
T45 Phosphorylation PhosphoSitePlus
K47 Ubiquitination PhosphoSitePlus
S52 Phosphorylation PhosphoSitePlus
C54 Methylation IEDB 31844290
C54 S-Nitrosylation dbSNO 22178444, 19366988, 18335467
C65 Methylation IEDB 31844290
T81 Phosphorylation PhosphoSitePlus
K85 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
A2 V2 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K8 E8 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
S52 F52 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T81 M81 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]