iPTMnet Report P14410 SI

Protein Information

Cytoscape View

UniProt AC / UniProt ID	P14410 / SUIS_HUMAN
Protein Name	Sucrase-isomaltase, intestinal
Gene Name	Name: SI
Organism	Homo sapiens (Human)

PRO ID	PR:P14410 DAG View
PRO Name	sucrase-isomaltase, intestinal (human)
Definition	A sucrase-isomaltase, intestinal that is encoded in the genome of human.
Short Label	hSI
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

P14410 (SI) as Substrate

P14410

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S7	Phosphorylation	P17612 (PRKACA)	score3	HPRD phospho.ELM UniProt	8521865
	T51	Phosphorylation		score1	PhosphoSitePlus
	N99	N-Glycosylation		score3	GlyGen UniProt	20356844
	Y190	Phosphorylation		score1	PhosphoSitePlus
	S200	Phosphorylation		score1	PhosphoSitePlus
	N455	N-Glycosylation		score3	GlyGen UniProt	20356844
	Y540	Phosphorylation		score1	PhosphoSitePlus
	Y795	Phosphorylation		score1	IEDB	35494241
	N855	N-Glycosylation		score3	GlyGen UniProt	20356844
	N904	N-Glycosylation		score3	GlyGen UniProt	20356844
	Y983	Phosphorylation		score1	PhosphoSitePlus
	S984	Phosphorylation		score1	PhosphoSitePlus
	S987	Phosphorylation		score1	PhosphoSitePlus
	S991	Phosphorylation		score1	PhosphoSitePlus
	T996	Phosphorylation		score1	PhosphoSitePlus
	T1003	Phosphorylation		score1	PhosphoSitePlus
	Y1587	Phosphorylation		score1	PhosphoSitePlus
	Y1592	Phosphorylation		score1	PhosphoSitePlus
	S1771	Phosphorylation		score1	PhosphoSitePlus

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
S7	C7	Biomuta		DOID:1324 / lung cancer [ cosmic ]
S7	I7	Biomuta		DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
T51	A51	Biomuta		DOID:1319 / brain cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic ]
S200	G200	Biomuta		DOID:1324 / lung cancer [ cosmic ]
S200	I200	Biomuta		DOID:1324 / lung cancer [ cosmic, icgc ]
S200	R200	Biomuta		DOID:1324 / lung cancer [ cosmic, icgc ]
N455	Y455	Biomuta		DOID:4159 / skin cancer [ cosmic ]
Y983	F983	Biomuta		DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S984	*	Biomuta		DOID:4159 / skin cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ]
S984	L984	Biomuta		DOID:4159 / skin cancer [ cosmic, icgc ]
S987	L987	Biomuta		DOID:1324 / lung cancer [ cosmic, icgc ]
S991	*	Biomuta		DOID:8618 / oral cavity cancer [ cosmic ] DOID:9253 / gastrointestinal stromal tumor [ cosmic ]
S1771	F1771	Biomuta		DOID:1793 / pancreatic cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic, icgc ]