iPTMnet Report for P13747 (HLA-E)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P13747 / HLAE_HUMAN
Protein Name HLA class I histocompatibility antigen, alpha chain E precursor
Gene Name Name: HLA-E
Synonyms:HLA-6.2,HLAE;
Organism Homo sapiens (Human)

PRO ID PR:P13747
DAG View
PRO Name HLA class I histocompatibility antigen, alpha chain E (human)
Definition An MHC class I histocompatibility antigen, alpha chain E that is encoded in the genome of human.
Short Label hHLA-E
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P13747 (HLA-E) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S23 Phosphorylation PhosphoSitePlus
S25 Phosphorylation PhosphoSitePlus
Y48 Phosphorylation PhosphoSitePlus
N107 N-Glycosylation GlyGen   UniProt 29741879, 24190977, 19349973
Y139 Phosphorylation PhosphoSitePlus
K142 Ubiquitination PhosphoSitePlus
N148 N-Glycosylation GlyGen 24190977
K167 Ubiquitination PhosphoSitePlus
K191 Ubiquitination PhosphoSitePlus
K195 Ubiquitination PhosphoSitePlus
K197 Ubiquitination PhosphoSitePlus
K207 Ubiquitination PhosphoSitePlus
S216 Phosphorylation PhosphoSitePlus
K264 Ubiquitination PhosphoSitePlus
S272 Phosphorylation PhosphoSitePlus
S333 Phosphorylation PhosphoSitePlus
K337 Ubiquitination PhosphoSitePlus
S340 Phosphorylation PhosphoSitePlus
Y341 Phosphorylation PhosphoSitePlus
S342 Phosphorylation PhosphoSitePlus
K343 Ubiquitination PhosphoSitePlus
S347 Phosphorylation PhosphoSitePlus
S357 Phosphorylation HPRD   PhosphoSitePlus 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N107 S107 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S357 R357 Biomuta DOID:1319 / brain cancer [ cosmic ]