iPTMnet Report P13646 KRT13

Protein Information

UniProt AC / UniProt ID	P13646 / K1C13_HUMAN
Protein Name	Keratin, type I cytoskeletal 13
Gene Name	Name: KRT13
Organism	Homo sapiens (Human)

PRO ID	PR:P13646 DAG View
PRO Name	keratin, type I cytoskeletal 13 (human)
Definition	A keratin, type I cytoskeletal 13 that is encoded in the genome of human.
Short Label	hKRT13
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

P13646 (KRT13) as Substrate

Expanded View

Site	PTM Type	Score	Source	PMID
S7	Phosphorylation	score1	PhosphoSitePlus
S8	Phosphorylation	score1	PhosphoSitePlus
S11	Phosphorylation	score1	PhosphoSitePlus
Y12	Phosphorylation	score1	PhosphoSitePlus
R27	Methylation	score2	PhosphoSitePlus UniProt	24129315
R35	Methylation	score2	PhosphoSitePlus UniProt	24129315
Y118	Phosphorylation	score1	PhosphoSitePlus
S144	Phosphorylation	score1	PhosphoSitePlus
S147	Phosphorylation	score1	PhosphoSitePlus
Y152	Phosphorylation	score1	PhosphoSitePlus
S153	Phosphorylation	score1	PhosphoSitePlus
Y155	Phosphorylation	score1	PhosphoSitePlus
Y156	Phosphorylation	score1	PhosphoSitePlus
T168	Phosphorylation	score1	PhosphoSitePlus
T170	Phosphorylation	score1	PhosphoSitePlus
Y194	Phosphorylation	score1	PhosphoSitePlus
Y238	Phosphorylation	score1	PhosphoSitePlus
Y281	Phosphorylation	score1	PhosphoSitePlus
R287	Methylation	score1	PhosphoSitePlus
R289	Methylation	score1	PhosphoSitePlus
T311	Phosphorylation	score1	PhosphoSitePlus
T316	Phosphorylation	score1	PhosphoSitePlus
T327	Phosphorylation	score1	PhosphoSitePlus
S337	Phosphorylation	score1	PhosphoSitePlus
S340	Phosphorylation	score1	PhosphoSitePlus
T404	Phosphorylation	score1	PhosphoSitePlus
Y405	Phosphorylation	score1	PhosphoSitePlus
S421	O-Glycosylation	score1	GlyGen	32574038
S421	Phosphorylation	score1	PhosphoSitePlus
S422	Phosphorylation	score1	PhosphoSitePlus
S425	Phosphorylation	score1	PhosphoSitePlus
S427	Phosphorylation	score2	phospho.ELM PhosphoSitePlus UniProt	17287340, 21406692, 23186163, ...17081983
S432	Phosphorylation	score1	PhosphoSitePlus
T434	Phosphorylation	score1	PhosphoSitePlus
T452	Phosphorylation	score1	PhosphoSitePlus
S453	Phosphorylation	score1	PhosphoSitePlus

Site	PTM Type	Score	Source	PMID
T327	Phosphorylation	score0	HPRD	20068231
S337	Phosphorylation	score0	HPRD	20068231
S422	Phosphorylation	score0	HPRD	20068231
S425	Phosphorylation	score0	HPRD	17081983
S427	Phosphorylation	score0	HPRD	17287340, 17081983, 19664995

Site	PTM Type	Score	Source	PMID
R27	Methylation	score1	PhosphoSitePlus
T327	Phosphorylation	score0	HPRD	20068231
S337	Phosphorylation	score0	HPRD	20068231
K416	Acetylation	score1	PhosphoSitePlus

PTM sites affected in variants

Site	Variant	Source	Disease [Sample source]
S7	N7	Biomuta	DOID:10283 / prostate cancer [ cosmic, icgc ]
S8	F8	Biomuta	DOID:4606 / bile duct cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic, cosmic ] DOID:4159 / skin cancer [ cosmic, cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ]
R27	C27	Biomuta	DOID:8618 / oral cavity cancer [ cosmic ]
R27	H27	Biomuta	DOID:4606 / bile duct cancer [ cosmic ]
R35	Q35	Biomuta	DOID:363 / uterine cancer [ cosmic, icgc ]
Y118	H118	Biomuta	DOID:4606 / bile duct cancer [ cosmic ]
Y118	C118	Biomuta	DOID:1324 / lung cancer [ cosmic, icgc ]
S144	N144	Biomuta	DOID:1319 / brain cancer [ cosmic ]
Y152	C152	Biomuta	DOID:11054 / urinary bladder cancer [ cosmic ]
Y152	*	Biomuta	DOID:5041 / esophageal cancer [ cosmic ]
S153	I153	Biomuta	DOID:9256 / colorectal cancer [ cosmic ]
S153	N153	Biomuta	DOID:4159 / skin cancer [ cosmic, icgc, tcga ]
Y155	H155	Biomuta	DOID:9256 / colorectal cancer [ cosmic ]
Y156	C156	Biomuta	DOID:1324 / lung cancer [ cosmic, icgc ]
Y281	H281	Biomuta	DOID:2531 / hematologic cancer [ cosmic ]
R287	G287	Biomuta	DOID:263 / kidney cancer [ cosmic, icgc ]
T327	M327	Biomuta	DOID:9256 / colorectal cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
S337	F337	Biomuta	DOID:4159 / skin cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic ]

PTM Type		Select All, None
Acetylation	N-Glycosylation	O-Glycosylation
C-Glycosylation	S-Glycosylation	Methylation
Myristoylation	Phosphorylation	Sumoylation
Ubiquitination	S-Nitrosylation

Select organisms		Select All, None
Human	Mouse	Rat
Cow	Chicken	Zebrafish
Fruit fly	C. elegans	Baker's yeast
Fission yeast	A. thaliana	Maize
M. truncatula	Rice (japonica)	Rice (indica)

Or input other organisms

iPTMnet Report for P13646 (KRT13)

Protein Information

Interactive Sequence View

P13646 (KRT13) as Substrate

PTM sites affected in variants