iPTMnet Report for P12757 (SKIL)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P12757 / SKIL_HUMAN
Protein Name Ski-like protein
Gene Name Name: SKIL
Synonyms:SNO;
Organism Homo sapiens (Human)

PRO ID PR:P12757
DAG View
PRO Name ski-like protein (human)
Definition A ski-like protein that is encoded in the genome of human.
Short Label hSKIL
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P12757 (SKIL) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T6 Phosphorylation PhosphoSitePlus
S26 Phosphorylation PhosphoSitePlus
K50 Sumoylation PhosphoSitePlus
K70 Ubiquitination PhosphoSitePlus
T72 O-Glycosylation GlyGen 30379171, 35289036, 35254053
T74 O-Glycosylation GlyGen 30379171, 35289036, 35254053
S75 O-Glycosylation GlyGen 30379171, 35289036, 35254053
K249 Ubiquitination PhosphoSitePlus
K256 Ubiquitination PhosphoSitePlus
C268 Methylation IEDB 31844290
K342 Ubiquitination PhosphoSitePlus
K343 Ubiquitination PhosphoSitePlus
K383 Sumoylation PhosphoSitePlus
K423 Ubiquitination PhosphoSitePlus
T426 Phosphorylation PhosphoSitePlus
K432 Acetylation PhosphoSitePlus
K440 Acetylation PhosphoSitePlus
K440 Ubiquitination PhosphoSitePlus
K446 Acetylation PhosphoSitePlus
K446 Ubiquitination PhosphoSitePlus
K449 Ubiquitination PhosphoSitePlus
S452 Phosphorylation PhosphoSitePlus   UniProt 23186163
S457 Phosphorylation PhosphoSitePlus
K463 Acetylation PhosphoSitePlus
K487 Methylation PhosphoSitePlus
K489 Sumoylation PhosphoSitePlus
S490 Phosphorylation PhosphoSitePlus
S514 Phosphorylation PhosphoSitePlus
K527 Sumoylation PhosphoSitePlus
K540 Ubiquitination PhosphoSitePlus
K552 Ubiquitination PhosphoSitePlus
K580 Ubiquitination PhosphoSitePlus
K601 Ubiquitination PhosphoSitePlus
K612 Ubiquitination PhosphoSitePlus
K625 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S26 Phosphorylation HPRD 19413330
T426 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T6 P6 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T72 S72 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K342 N342 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
K440 R440 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
K449 I449 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S514 F514 Biomuta DOID:4159 / skin cancer [ cosmic ]