iPTMnet Report for P12110 (COL6A2)
Protein Information
UniProt AC / UniProt ID | P12110 / CO6A2_HUMAN |
Protein Name | Collagen alpha-2(VI) chain precursor |
Gene Name | Name: COL6A2 |
Organism | Homo sapiens (Human) |
PRO ID | PR:P12110 |
PRO Name | collagen alpha-2(VI) chain (human) |
Definition | A collagen alpha-2(VI) chain that is encoded in the genome of human. |
Short Label | hCOL6A2 |
Category | organism-gene |
P12110 (COL6A2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
C43 | Methylation | score1 | IEDB | 31844290 | ||
T58 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
K120 | Ubiquitination | score1 | PhosphoSitePlus | |||
S126 | Phosphorylation | score1 | PhosphoSitePlus | |||
S127 | Phosphorylation | score1 | PhosphoSitePlus | |||
N140 | N-Glycosylation | score2 | GlyGen UniProt | 23090970, 29741879, 19159218, ... | ||
K197 | Ubiquitination | score1 | PhosphoSitePlus | |||
T207 | Phosphorylation | score1 | PhosphoSitePlus | |||
T218 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
S223 | Phosphorylation | score1 | PhosphoSitePlus | |||
K393 | Ubiquitination | score1 | PhosphoSitePlus | |||
S399 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y597 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18083107 | ||
K609 | Acetylation | score1 | PhosphoSitePlus | |||
N630 | N-Glycosylation | score1 | GlyGen | 29741879 | ||
Y665 | Phosphorylation | score1 | PhosphoSitePlus | |||
S666 | Phosphorylation | score1 | PhosphoSitePlus | |||
S683 | Phosphorylation | score1 | PhosphoSitePlus | |||
S685 | Phosphorylation | score1 | PhosphoSitePlus | |||
K688 | Ubiquitination | score1 | PhosphoSitePlus | |||
K692 | Ubiquitination | score1 | PhosphoSitePlus | |||
T701 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 19690332 | ||
T703 | Phosphorylation | score1 | PhosphoSitePlus | |||
S705 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
C748 | Methylation | score1 | IEDB | 31844290 | ||
C777 | Methylation | score1 | IEDB | 31844290 | ||
N785 | N-Glycosylation | score2 | GlyGen UniProt | 23090970, 29741879, 19159218, ... | ||
T787 | O-Glycosylation | score1 | GlyGen | 23271734, 28657654 | ||
C806 | Methylation | score1 | IEDB | 31844290 | ||
K851 | Ubiquitination | score1 | PhosphoSitePlus | |||
N897 | N-Glycosylation | score2 | GlyGen UniProt | 19159218 | ||
N954 | N-Glycosylation | score2 | GlyGen UniProt | 29741879, 19159218 | ||
K1000 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
C43 | F43 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
T58 | I58 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
S126 | G126 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
S127 | F127 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
T207 | M207 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
S399 | N399 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] | |
Y597 | D597 | Biomuta | DOID:263 / kidney cancer [ icgc ] | |
S683 | F683 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
C777 | R777 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
N785 | S785 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:263 / kidney cancer [ icgc, icgc ] |