iPTMnet Report for P11978 (SIR4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P11978 / SIR4_YEAST
Protein Name Regulatory protein SIR4
Gene Name Name: SIR4
Synonyms:ASD1,STE9,UTH2;OrderedLocusNames:YDR227W;ORFNames:YD9934.12;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

PRO ID PR:P11978
DAG View
PRO Name regulatory protein SIR4 (yeast)
Definition A protein that is a translation product of the SIR4 gene in yeast.
Short Label ySIR4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P11978 (SIR4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T7 Phosphorylation SGD 33491328
K15 Sumoylation SGD 33502312
K19 Sumoylation SGD 33502312
T22 Phosphorylation SGD 22654676, 32597660, 33481703, ...33491328
K26 Sumoylation SGD 33502312
T39 Phosphorylation SGD 23749301
K49 Sumoylation SGD 33502312
K51 Sumoylation SGD 33502312
Y53 Phosphorylation SGD 33502312
S54 Phosphorylation SGD 33502312
S57 Phosphorylation SGD 33502312
T58 Phosphorylation SGD 33502312
T62 Phosphorylation BioGRID   SGD 33502312, 17287358
S63 Phosphorylation SGD 33502312, 22654676
K71 Sumoylation SGD 33502312
K82 Sumoylation SGD 33502312
S83 Phosphorylation BioGRID   SGD 19795423, 33491328, 19823750
S84 Phosphorylation BioGRID   SGD 22654676, 19795423, 19823750, ...33491328
K106 Sumoylation SGD 33502312
S135 Phosphorylation SGD 33491328
S181 Phosphorylation SGD 33491328
K184 Sumoylation SGD 33502312
K226 Sumoylation SGD 33502312
K237 Sumoylation SGD 33502312
K240 Sumoylation SGD 33502312
S263 Phosphorylation SGD 33491328
S266 Phosphorylation SGD 33491328
S270 Phosphorylation SGD 32597660
S274 Phosphorylation SGD 33491328, 18407956
S342 Phosphorylation BioGRID   SGD 22654676, 18407956, 23749301, ...19779198, 32597660, 33491328
S342 Phosphorylation P00546 (CDC28) BioGRID 19779198, 18407956
S342 Phosphorylation P24869 (CLB2) BioGRID 19779198, 18407956
K359 Sumoylation SGD 33502312
S389 Phosphorylation BioGRID   SGD 19779198, 22654676, 33491328
S389 Phosphorylation P00546 (CDC28) BioGRID 19779198
S389 Phosphorylation P24869 (CLB2) BioGRID 19779198
S393 Phosphorylation SGD 33491328
S395 Phosphorylation SGD 33491328
T514 Phosphorylation BioGRID   SGD 22654676, 33481703, 19520826
S516 Phosphorylation SGD 33481703
K600 Sumoylation SGD 33502312
S611 Phosphorylation SGD 33481703, 33491328
K633 Sumoylation SGD 33502312
K638 Sumoylation SGD 33502312
S639 Phosphorylation SGD 33491328
K649 Sumoylation SGD 33502312
K654 Sumoylation SGD 33502312
K658 Sumoylation SGD 33502312
K685 Sumoylation SGD 33502312
S690 Phosphorylation SGD 33491328
S692 Phosphorylation BioGRID   SGD   UniProt 33481703, 18407956, 23749301, ...20190278, 32597660, 33491328
S692 Phosphorylation P38110 (TEL1) BioGRID 20190278, 18407956
S692 Phosphorylation P38111 (MEC1) BioGRID 20190278, 18407956
S696 Phosphorylation SGD 33481703
K699 Sumoylation SGD 33502312
S709 Phosphorylation BioGRID   SGD 18407956
S711 Phosphorylation SGD 33491328, 18407956
S717 Phosphorylation SGD 33491328
T722 Phosphorylation SGD 33481703, 33491328
T739 Phosphorylation SGD 33481703
T787 Phosphorylation SGD 33481703
S788 Phosphorylation SGD 33481703, 33491328, 18407956, ...23749301
K791 Sumoylation SGD 33502312
K877 Sumoylation SGD 33502312
K878 Sumoylation SGD 33502312
K906 Sumoylation SGD 33502312
S914 Phosphorylation SGD 33491328
S931 Phosphorylation SGD 33481703
S932 Phosphorylation SGD 22654676, 33481703, 33491328
T944 Phosphorylation SGD 32597660, 23749301, 33491328
T946 Phosphorylation SGD 33491328
S953 Phosphorylation SGD 32597660, 33491328
S1133 Phosphorylation BioGRID   SGD 21177495, 33481703
S1134 Phosphorylation BioGRID   SGD 33481703, 17563356, 17330950, ...22654676, 18407956, 23749301, 19779198, 32597660, 33491328
K1139 Sumoylation SGD 33502312
K1150 Sumoylation SGD 33502312
K1256 Sumoylation SGD 33502312
K1267 Sumoylation SGD 33502312