Protein Information

Cytoscape View


UniProt AC / UniProt ID P11912 / CD79A_HUMAN
Protein Name B-cell antigen receptor complex-associated protein alpha chain precursor
Gene Name Name: CD79A
Synonyms:IGA,MB1;
Organism Homo sapiens (Human)

PRO ID PR:P11912
DAG View
PRO Name B-cell antigen receptor complex-associated protein alpha chain (human)
Definition A B-cell antigen receptor complex-associated protein alpha chain that is encoded in the genome of human.
Short Label hCD79A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P11912 (CD79A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N57 N-Glycosylation GlyGen 24190977
N60 N-Glycosylation GlyGen 24190977
N61 N-Glycosylation GlyGen 24190977
N63 N-Glycosylation GlyGen 24190977
N73 N-Glycosylation GlyGen 24190977
N88 N-Glycosylation GlyGen 24190977
N95 N-Glycosylation GlyGen 24190977
N97 N-Glycosylation GlyGen 24190977
N112 N-Glycosylation GlyGen 29741879, 24190977
C119 Methylation IEDB 31844290
T140 Phosphorylation PhosphoSitePlus
K141 Ubiquitination PhosphoSitePlus
T161 Phosphorylation PhosphoSitePlus
K173 Ubiquitination PhosphoSitePlus
Y182 Phosphorylation phospho.ELM   PhosphoSitePlus 11909947
Y188 Phosphorylation P51451 (BLK) , P07948 (LYN) neXtProt   phospho.ELM   PRO   PhosphoSitePlus   RLIMS-P 24769851, 9531288, 7592958
S197 Phosphorylation P43405 (SYK) PhosphoSitePlus   RLIMS-P+ 20940318
Y199 Phosphorylation P51451 (BLK) , P06241 (FYN) neXtProt   phospho.ELM   PRO   PhosphoSitePlus   RLIMS-P 24769851, 9531288, 7592958
S203 Phosphorylation P43405 (SYK) neXtProt 20940318, 7538118
T209 Phosphorylation PhosphoSitePlus
Y210 Phosphorylation phospho.ELM   PhosphoSitePlus 11909947
S215 Phosphorylation PhosphoSitePlus
K225 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y188 Phosphorylation P07948 (LYN) HPRD 9531288
Y199 Phosphorylation P06241 (FYN) HPRD 9531288
Site PTM Type PTM Enzyme Score Source PMID
Y150 Phosphorylation P07948 (LYN) HPRD 9531288
Y161 Phosphorylation P06241 (FYN) HPRD 9531288


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000046647 (hCD79A/SigPep-/Phos:1) pY188,pY199 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N63 S63 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic ]
C119 R119 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
T140 N140 Biomuta DOID:363 / uterine cancer [ cosmic ]
K141 N141 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
Y150 * Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y150 F150 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y150 D150 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y150 H150 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y150 N150 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y161 * Biomuta DOID:2531 / hematologic cancer [ cosmic ]
T161 M161 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:2394 / ovarian cancer [ cosmic, icgc ]
Y182 N182 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y182 H182 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y182 C182 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y182 * Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y188 * Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y188 N188 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y188 H188 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y188 F188 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y188 D188 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y199 * Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S203 F203 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S203 T203 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]