iPTMnet Report for P11798 (Camk2a)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P11798 / KCC2A_MOUSE
Protein Name Calcium/calmodulin-dependent protein kinase type II subunit alpha
Gene Name Name: Camk2a
Organism Mus musculus (Mouse)

PRO ID PR:P11798
DAG View
PRO Name calcium/calmodulin-dependent protein kinase type II subunit alpha (mouse)
Definition A calcium/calmodulin-dependent protein kinase type II subunit alpha that is encoded in the genome of mouse.
Short Label mCAMK2A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P11798 (Camk2a) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T10 Phosphorylation PhosphoSitePlus
Y13 Phosphorylation PhosphoSitePlus   UniProt 18034455
K21 Ubiquitination PhosphoSitePlus
S25 Phosphorylation phospho.ELM   PhosphoSitePlus 15648052
K32 Ubiquitination PhosphoSitePlus
Y39 Phosphorylation PhosphoSitePlus
K42 Acetylation PhosphoSitePlus
K42 Ubiquitination PhosphoSitePlus
K47 Acetylation PhosphoSitePlus
K47 Ubiquitination PhosphoSitePlus
K48 Ubiquitination PhosphoSitePlus
K68 Ubiquitination PhosphoSitePlus
K137 Ubiquitination PhosphoSitePlus
S145 Phosphorylation PhosphoSitePlus
K146 Ubiquitination PhosphoSitePlus
K148 Ubiquitination PhosphoSitePlus
K226 Ubiquitination PhosphoSitePlus
Y230 Phosphorylation PhosphoSitePlus
S234 Phosphorylation PhosphoSitePlus
K245 Ubiquitination PhosphoSitePlus
K250 Ubiquitination PhosphoSitePlus
T253 O-Glycosylation GlyGen   PhosphoSitePlus 22645316
T253 Phosphorylation PhosphoSitePlus
S257 Phosphorylation PhosphoSitePlus
K258 Acetylation PhosphoSitePlus
K258 Ubiquitination PhosphoSitePlus
K267 Ubiquitination PhosphoSitePlus
S272 Phosphorylation PhosphoSitePlus
S275 Phosphorylation phospho.ELM   PhosphoSitePlus 17114649
T276 Phosphorylation PhosphoSitePlus
S279 Phosphorylation PhosphoSitePlus
C280 S-Nitrosylation dbSNO 19101475
T286 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 15140879, 24374198, 28130356, ...24349346, 19257910, 10087064, 12379661, 17114649, 23516528
T286 Phosphorylation P11798 (Camk2a) PhosphoSitePlus   UniProt 12379661, 23516528, 10087064, ...28130356
K291 Ubiquitination PhosphoSitePlus
K292 Ubiquitination PhosphoSitePlus
K298 Methylation PhosphoSitePlus
K300 Methylation PhosphoSitePlus
K300 Ubiquitination PhosphoSitePlus
T305 O-Glycosylation GlyGen 34678516
T305 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P 12379661, 27799554, 22363696, ...12408851
T305 Phosphorylation P11798 (Camk2a) PhosphoSitePlus 12379661
T306 O-Glycosylation GlyGen   PhosphoSitePlus 34678516, 22645316, 28657654
T306 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P 12379661, 27799554, 12408851
T306 Phosphorylation P11798 (Camk2a) PhosphoSitePlus 12379661
T310 Phosphorylation PhosphoSitePlus
S314 Phosphorylation PhosphoSitePlus
S318 Phosphorylation PhosphoSitePlus
K328 Ubiquitination PhosphoSitePlus
S330 Phosphorylation PhosphoSitePlus   UniProt 21183079
S331 Phosphorylation PhosphoSitePlus   UniProt 21183079
S333 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21183079, 17114649, 15572359
T334 Phosphorylation phospho.ELM   PhosphoSitePlus 17114649
T336 Phosphorylation PhosphoSitePlus   UniProt 21183079
T337 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17114649, 21183079
T343 Phosphorylation PhosphoSitePlus
K344 Ubiquitination PhosphoSitePlus
S404 Phosphorylation PhosphoSitePlus   UniProt 21183079
S470 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S53 Phosphorylation PhosphoSitePlus
S55 Phosphorylation PhosphoSitePlus


P11798 (Camk2a) as PTM Enzyme



Substrate Site Score Source PMID
E9Q401 (Ryr2) S2813 PhosphoSitePlus 23516528, 21098440
O70468 (Mybpc3) S25 PhosphoSitePlus 23619294
O70468 (Mybpc3) S47 PhosphoSitePlus 23619294
O70468 (Mybpc3) T50 PhosphoSitePlus 23619294
O70468 (Mybpc3) S105 PhosphoSitePlus 23619294
O70468 (Mybpc3) S210 PhosphoSitePlus 23619294
O70468 (Mybpc3) S273 PhosphoSitePlus 23619294
O70468 (Mybpc3) S282 PhosphoSitePlus 23619294
O70468 (Mybpc3) T290 PhosphoSitePlus 23619294
O70468 (Mybpc3) S307 PhosphoSitePlus 23619294
O70468 (Mybpc3) T380 PhosphoSitePlus 23619294
O70468 (Mybpc3) S410 PhosphoSitePlus 23619294
P08551 (Nefl) S58 PhosphoSitePlus 10854283
P11798 (Camk2a) T286 PhosphoSitePlus   UniProt 12379661, 23516528, 10087064, ...28130356
P11798 (Camk2a) T305 PhosphoSitePlus 12379661
P11798 (Camk2a) T306 PhosphoSitePlus 12379661
P18052 (Ptpra) S180 PhosphoSitePlus 18809727
P18052 (Ptpra) S204 PhosphoSitePlus 18809727
P20152 (Vim) S83 PhosphoSitePlus 15140879
P23818 (Gria1) S849 PhosphoSitePlus 21516102, 25381005
P27699 (Crem) S133 PhosphoSitePlus 8404858
P34152-3 (Ptk2) S843 PhosphoSitePlus 15845548
P54227 (Stmn1) S16 PhosphoSitePlus 19688729
P61014 (Pln) S16 PhosphoSitePlus 10988285
P61014 (Pln) T17 PhosphoSitePlus 10988285
Q00560 (Il6st) S780 PhosphoSitePlus 16036214
Q01815 (Cacna1c) S1487 PhosphoSitePlus 20479240
Q01815 (Cacna1c) S1545 PhosphoSitePlus 20479240
Q62048 (Pea15) S116 PhosphoSitePlus 9721757
Q8VHH7 (Adcy3) S1077 PhosphoSitePlus 9768837
Q99PW8 (Kif17) S1029 PhosphoSitePlus 18066053
Q9QWW1 (Homer2) S216 PhosphoSitePlus 26670047
Q9WV18 (Gabbr1) S867 PhosphoSitePlus 20643921
Q9Z2Y3 (Homer1) S117 PhosphoSitePlus 26670047


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P11798 (Camk2a) T286 Q6R891 (Ppp1r9b) increased_association eFIP 22348105