iPTMnet Report for P11678 (EPX)
Protein Information
UniProt AC / UniProt ID | P11678 / PERE_HUMAN |
Protein Name | Eosinophil peroxidase precursor |
Gene Name | Name: EPX Synonyms:EPER,EPO,EPP; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P11678 |
PRO Name | eosinophil peroxidase (human) |
Definition | An eosinophil peroxidase that is encoded in the genome of human. |
Short Label | hEPX |
Category | organism-gene |
P11678 (EPX) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S66 | Phosphorylation | score1 | PhosphoSitePlus | |||
S74 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y75 | Phosphorylation | score1 | PhosphoSitePlus | |||
S322 | Phosphorylation | score1 | PhosphoSitePlus | |||
N327 | N-Glycosylation | score2 | GlyGen | 10864452 | ||
N363 | N-Glycosylation | score3 | GlyGen | 29741879, 10864452 | ||
C370 | S-Nitrosylation | score0 | dbSNO | 25040305 | ||
Y431 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y451 | Phosphorylation | score1 | PhosphoSitePlus | |||
K594 | Methylation | score1 | PhosphoSitePlus | |||
C635 | S-Nitrosylation | score0 | dbSNO | 25040305 | ||
S670 | Phosphorylation | score1 | PhosphoSitePlus | |||
S672 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S66 | L66 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
Y75 | * | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S322 | L322 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] | |
Y451 | * | Biomuta | DOID:1319 / brain cancer [ cosmic ] |