iPTMnet Report for P11166 (SLC2A1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P11166 / GTR1_HUMAN
Protein Name Solute carrier family 2, facilitated glucose transporter member 1
Gene Name Name: SLC2A1
Synonyms:GLUT1;
Organism Homo sapiens (Human)

PRO ID PR:P11166
DAG View
PRO Name solute carrier family 2, facilitated glucose transporter member 1 (human)
Definition A solute carrier family 2, facilitated glucose transporter member 1 that is encoded in the genome of human.
Short Label hSLC2A1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P11166 (SLC2A1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
N45 N-Glycosylation GlyGen   UniProt 19349973, 3839598, 24190977
S118 Phosphorylation HPRD   PhosphoSitePlus 20068231
S226 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 25982116
T234 Phosphorylation PhosphoSitePlus
T238 Phosphorylation PhosphoSitePlus
K245 Ubiquitination PhosphoSitePlus
T258 Phosphorylation PhosphoSitePlus
S465 O-Glycosylation GlyGen   PhosphoSitePlus 18984734, 34725712, 35083852, ...34019948
S465 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 19664994
S473 Phosphorylation HPRD   PhosphoSitePlus 18691976, 20068231
K477 Sumoylation PhosphoSitePlus
K477 Ubiquitination PhosphoSitePlus
T478 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18578522, 20068231
S490 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 17525332, 23186163, 30799198, ...19664994, 18578522, 19651622, 21406692, 24275569, 25101238


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N45 S45 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S118 F118 Biomuta DOID:4362 / cervical cancer [ cosmic ]
S473 R473 Biomuta DOID:3571 / liver cancer [ cosmic ]