iPTMnet Report for P10619 (CTSA)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P10619 / PPGB_HUMAN
Protein Name Lysosomal protective protein precursor
Gene Name Name: CTSA
Synonyms:PPGB;
Organism Homo sapiens (Human)

PRO ID PR:P10619
DAG View
PRO Name lysosomal protective protein (human)
Definition A lysosomal protective protein that is encoded in the genome of human.
Short Label hCTSA
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P10619 (CTSA) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K55 Methylation PhosphoSitePlus
N145 N-Glycosylation GlyGen   UniProt 16263699, 29741879, 19159218, ...24190977
N153 N-Glycosylation GlyGen 24190977
N244 N-Glycosylation GlyGen 24190977
T295 Phosphorylation PhosphoSitePlus
N333 N-Glycosylation GlyGen   UniProt 29741879, 19159218, 24190977
N351 N-Glycosylation GlyGen 23090970, 24190977
K429 Acetylation IEDB 34357683
K429 Ubiquitination PhosphoSitePlus
Y430 Phosphorylation PhosphoSitePlus
K442 Acetylation IEDB 34357683
T469 Phosphorylation PhosphoSitePlus
S472 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N333 K333 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T469 A469 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S472 Y472 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]