iPTMnet Report for P09769 (FGR)
Protein Information
| UniProt AC / UniProt ID | P09769 / FGR_HUMAN |
| Protein Name | Tyrosine-protein kinase Fgr |
| Gene Name | Name: FGR Synonyms:SRC2; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P09769 |
| PRO Name | tyrosine-protein kinase Fgr (human) |
| Definition | A tyrosine-protein kinase Fgr that is encoded in the genome of human. |
| Short Label | hFGR |
| Category | organism-gene |
DAG ViewP09769 (FGR) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K16 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y28 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus | 18083107 | ||
| Y34 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus UniProt | 18083107, 19369195 | ||
| Y86 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S173 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T176 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K177 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y180 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S181 | O-Glycosylation | score1 | GlyGen | 35254053 | ||
| S181 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S183 | O-Glycosylation | score1 | GlyGen | 35254053 | ||
| S183 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y208 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus | 18083107 | ||
| Y209 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T211 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T212 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S261 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S262 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T292 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K301 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S341 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y412 | Phosphorylation | P09769 (FGR) | score4 | HPRD neXtProt phospho.ELM PhosphoSitePlus UniProt | 18083107, 8612628, 7515063, ... | |
| T453 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y459 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y523 | Phosphorylation | P41240 (CSK) , P09769 (FGR) | score4 | HPRD neXtProt phospho.ELM PhosphoSitePlus UniProt | 19369195, 8612628, 7515063 |
P09769 (FGR) as PTM Enzyme
|
Substrate | Site | Score | Source | PMID |
|---|---|---|---|---|---|
| P09769 (FGR) | Y412 | score4 | HPRD neXtProt phospho.ELM | 8612628, 7515063 | |
| P09769 (FGR) | Y523 | score2 | neXtProt | 7515063 | |
| P12931-1 (SRC) | Y530 | score2 | HPRD | 12387813, 12468645, 9208935, ... | |
| P14317 (HCLS1) | Y222 | score3 | HPRD neXtProt phospho.ELM | 10066823 | |
| P14317 (HCLS1) | Y397 | score2 | phospho.ELM | 9183008 | |
| P31040 (SDHA) | Y543 | score2 | neXtProt | 17997986 | |
| P31040 (SDHA) | Y604 | score2 | neXtProt | 17997986 | |
| P37840-1 (SNCA) | Y125 | score2 | HPRD | 12096713, 11162638, 11744621 | |
| P68400 (CSNK2A1) | Y255 | score3 | neXtProt phospho.ELM | 12628006 | |
| Q05397 (PTK2) | Y397 | score4 | neXtProt PhosphoSitePlus | 15561106, 12387730 | |
| Q05397 (PTK2) | Y576 | score4 | neXtProt PhosphoSitePlus | 12387730, 15561106 | |
| Q05397 (PTK2) | Y925 | score3 | neXtProt PhosphoSitePlus Signor | 12387730 | |
| Q99798 (ACO2) | Y71 | score2 | neXtProt | 17997986 | |
| Q99798 (ACO2) | Y544 | score2 | neXtProt | 17997986 | |
| Q99798 (ACO2) | Y665 | score2 | neXtProt | 17997986 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S181 | F181 | Biomuta | DOID:263 / kidney cancer [ icgc ] | |
| S261 | G261 | Biomuta | DOID:1612 / breast cancer [ icgc ] | |
| T453 | P453 | Biomuta | DOID:4159 / skin cancer [ icgc ] |
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