iPTMnet Report for P09497 (CLTB)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P09497 / CLCB_HUMAN
Protein Name Clathrin light chain B
Gene Name Name: CLTB
Organism Homo sapiens (Human)

PRO ID PR:P09497
DAG View
PRO Name clathrin light chain B (human)
Definition A clathrin light chain B that is encoded in the genome of human.
Short Label hCLTB
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P09497 (CLTB) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S11 Phosphorylation RLIMS-P 3128543
S13 Phosphorylation RLIMS-P 3128543
Y87 Phosphorylation PhosphoSitePlus
K122 Ubiquitination PhosphoSitePlus
K134 Ubiquitination PhosphoSitePlus
K184 Ubiquitination PhosphoSitePlus
T187 Phosphorylation PhosphoSitePlus   UniProt 23186163
T190 Phosphorylation PhosphoSitePlus
K194 Methylation PhosphoSitePlus
K194 Ubiquitination PhosphoSitePlus
K204 Methylation PhosphoSitePlus
K204 Ubiquitination PhosphoSitePlus
S205 Phosphorylation P25098 (GRK2) PhosphoSitePlus   Signor 22704991
K207 Methylation PhosphoSitePlus
K207 Ubiquitination PhosphoSitePlus
S217 Phosphorylation PhosphoSitePlus
S221 Phosphorylation PhosphoSitePlus
K223 Ubiquitination PhosphoSitePlus
T225 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S11 Phosphorylation P68400 (CSNK2A1) , P19784 (CSNK2A2) HPRD 2874131, 3128543
S13 Phosphorylation P68400 (CSNK2A1) , P19784 (CSNK2A2) HPRD 2874131, 3128543
Site PTM Type PTM Enzyme Score Source PMID
S11 Phosphorylation P68400 (CSNK2A1) , P19784 (CSNK2A2) HPRD 2874131, 3128543
S13 Phosphorylation P19784 (CSNK2A2) , P68400 (CSNK2A1) HPRD 2874131, 3128543
S157 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S157 F157 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K184 N184 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S205 N205 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T225 M225 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1725 / peritoneum cancer [ cosmic ]