iPTMnet Report for P09467 (FBP1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P09467 / F16P1_HUMAN
Protein Name Fructose-1,6-bisphosphatase 1
Gene Name Name: FBP1
Synonyms:FBP;
Organism Homo sapiens (Human)

PRO ID PR:P09467
DAG View
PRO Name fructose-1,6-bisphosphatase 1 (human)
Definition A fructose-1,6-bisphosphatase 1 that is encoded in the genome of human.
Short Label hFBP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P09467 (FBP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T28 Phosphorylation PhosphoSitePlus
Y58 Phosphorylation PhosphoSitePlus
S63 Phosphorylation PhosphoSitePlus
K72 Acetylation PhosphoSitePlus
S88 Phosphorylation PhosphoSitePlus
K110 Acetylation PhosphoSitePlus
K113 Acetylation PhosphoSitePlus
S124 O-Glycosylation PhosphoSitePlus
S144 Phosphorylation PhosphoSitePlus   RLIMS-P 32754266
S170 Phosphorylation PhosphoSitePlus   RLIMS-P 36266488
Y216 Phosphorylation PhosphoSitePlus
Y227 Phosphorylation PhosphoSitePlus
K232 Acetylation PhosphoSitePlus
Y241 Phosphorylation PhosphoSitePlus
Y245 Phosphorylation PhosphoSitePlus
T256 Phosphorylation PhosphoSitePlus
Y259 Phosphorylation PhosphoSitePlus
Y265 Phosphorylation PhosphoSitePlus   UniProt 24275569
K269 Acetylation PhosphoSitePlus
S271 Phosphorylation PhosphoSitePlus
T297 Phosphorylation PhosphoSitePlus
T298 Phosphorylation PhosphoSitePlus
S321 Phosphorylation PhosphoSitePlus
K330 Acetylation PhosphoSitePlus


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P09467 (FBP1) S144 Q04206 (RELA) unknown eFIP 32754266


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K113 * Biomuta DOID:4159 / skin cancer [ cosmic ]
S144 * Biomuta DOID:1324 / lung cancer [ cosmic ]
Y216 C216 Biomuta DOID:10534 / stomach cancer [ cosmic ]
Y241 H241 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
T256 A256 Biomuta DOID:10534 / stomach cancer [ icgc ]
T297 A297 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K330 N330 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]