iPTMnet Report for P09417 (QDPR)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P09417 / DHPR_HUMAN
Protein Name Dihydropteridine reductase
Gene Name Name: QDPR
Synonyms:DHPR,SDR33C1;
Organism Homo sapiens (Human)

PRO ID PR:P09417
DAG View
PRO Name dihydropteridine reductase (human)
Definition A dihydropteridine reductase that is encoded in the genome of human.
Short Label hQDPR
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P09417 (QDPR) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 22814378, 22223895
R11 Methylation PhosphoSitePlus
Y16 Phosphorylation PhosphoSitePlus
S97 Phosphorylation PhosphoSitePlus
K109 Methylation PhosphoSitePlus
T123 Phosphorylation PhosphoSitePlus
T133 Phosphorylation PhosphoSitePlus
K138 Ubiquitination PhosphoSitePlus
T184 Phosphorylation PhosphoSitePlus
T187 Phosphorylation PhosphoSitePlus
S193 Phosphorylation PhosphoSitePlus
T203 Phosphorylation PhosphoSitePlus
S223 Phosphorylation phospho.ELM   PhosphoSitePlus 8137944
Site PTM Type PTM Enzyme Score Source PMID
T133 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
A2 V2 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
A2 S2 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S97 F97 Biomuta DOID:4159 / skin cancer [ cosmic, icgc, tcga ]