iPTMnet Report for P09382 (LGALS1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P09382 / LEG1_HUMAN
Protein Name Galectin-1
Gene Name Name: LGALS1
Organism Homo sapiens (Human)

PRO ID PR:P09382
DAG View
PRO Name galectin-1 (human)
Definition A galectin-1 that is encoded in the genome of human.
Short Label hLGALS1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P09382 (LGALS1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378, 22223895, 25944712
S8 Phosphorylation PhosphoSitePlus
K13 Ubiquitination PhosphoSitePlus
C17 Methylation IEDB 31844290
K29 Acetylation PhosphoSitePlus   UniProt 19608861
K29 Ubiquitination PhosphoSitePlus
S30 Phosphorylation HPRD   PhosphoSitePlus   UniProt 26091039, 20068231
K37 Ubiquitination PhosphoSitePlus
S39 Phosphorylation PhosphoSitePlus
C43 S-Nitrosylation dbSNO 2212679, 22126794, 22178444, ...20140087
T58 Phosphorylation PhosphoSitePlus
C61 S-Nitrosylation dbSNO 2212679, 18335467, 20140087, ...22126794, 22178444, 19366988
S63 Phosphorylation PhosphoSitePlus
K64 Acetylation PhosphoSitePlus
K64 Ubiquitination PhosphoSitePlus
T71 Phosphorylation PhosphoSitePlus
Y105 Phosphorylation PhosphoSitePlus
K108 Acetylation PhosphoSitePlus
K108 Sumoylation PhosphoSitePlus
K108 Ubiquitination PhosphoSitePlus
N119 N-Glycosylation GlyGen 24190977
Y120 Phosphorylation PhosphoSitePlus
K128 Acetylation PhosphoSitePlus
K128 Ubiquitination PhosphoSitePlus
K130 Acetylation PhosphoSitePlus
K130 Ubiquitination PhosphoSitePlus
C131 S-Nitrosylation dbSNO 22126794


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S8 I8 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K29 N29 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
K29 E29 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
S39 N39 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
C43 Y43 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T71 I71 Biomuta DOID:4159 / skin cancer [ cosmic ]
T71 A71 Biomuta [ cosmic ]
N119 D119 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K128 Q128 Biomuta DOID:5041 / esophageal cancer [ cosmic ]