iPTMnet Report for P09012 (SNRPA)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P09012 / SNRPA_HUMAN
Protein Name U1 small nuclear ribonucleoprotein A
Gene Name Name: SNRPA
Organism Homo sapiens (Human)

PRO ID PR:P09012
DAG View
PRO Name U1 small nuclear ribonucleoprotein A (human)
Definition A U1 small nuclear ribonucleoprotein A that is encoded in the genome of human.
Short Label hSNRPA
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P09012 (SNRPA) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330
K20 Ubiquitination PhosphoSitePlus
Y31 Phosphorylation PhosphoSitePlus
K60 Acetylation PhosphoSitePlus   UniProt 19608861
K60 Ubiquitination PhosphoSitePlus
K80 Acetylation PhosphoSitePlus
K88 Ubiquitination PhosphoSitePlus
S91 Phosphorylation PhosphoSitePlus
K96 Acetylation PhosphoSitePlus
K96 Ubiquitination PhosphoSitePlus
K98 Ubiquitination PhosphoSitePlus
S115 Phosphorylation PhosphoSitePlus
T118 Phosphorylation PhosphoSitePlus
K122 Acetylation PhosphoSitePlus
T131 O-Glycosylation GlyGen 33214551, 30379171, 34725712, ...30059200, 35254053, 34019948, 31492838, 31373491, 29485866, 32119511, 36240223, 35289036, 29237092
T131 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
T148 O-Glycosylation GlyGen 33214551, 32938750, 30379171, ...34725712, 30059200, 35254053, 34019948, 31492838, 31373491, 29485866, 32119511, 36240223, 35289036, 29237092
R152 Methylation PhosphoSitePlus   UniProt 24129315
K268 Ubiquitination PhosphoSitePlus
K276 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K20 N20 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S91 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
R152 S152 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
R152 H152 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic ] DOID:4362 / cervical cancer [ icgc ]
R152 C152 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]