iPTMnet Report for P08779 (KRT16)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P08779 / K1C16_HUMAN
Protein Name Keratin, type I cytoskeletal 16
Gene Name Name: KRT16
Synonyms:KRT16A;
Organism Homo sapiens (Human)

PRO ID PR:P08779
DAG View
PRO Name keratin, type I cytoskeletal 16 (human)
Definition A keratin, type I cytoskeletal 16 that is encoded in the genome of human.
Short Label hKRT16
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P08779 (KRT16) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T9 Phosphorylation PhosphoSitePlus
S10 Phosphorylation PhosphoSitePlus
S12 Phosphorylation PhosphoSitePlus
S13 Phosphorylation PhosphoSitePlus
K15 Methylation PhosphoSitePlus
S17 Phosphorylation PhosphoSitePlus
S28 Phosphorylation PhosphoSitePlus
S32 Phosphorylation PhosphoSitePlus
S33 Phosphorylation PhosphoSitePlus
S39 Phosphorylation PhosphoSitePlus
S44 Phosphorylation PhosphoSitePlus
T45 Phosphorylation PhosphoSitePlus
Y46 Phosphorylation PhosphoSitePlus
S51 Phosphorylation PhosphoSitePlus
S54 Phosphorylation PhosphoSitePlus
S130 Phosphorylation PhosphoSitePlus
Y131 Phosphorylation PhosphoSitePlus
K134 Acetylation PhosphoSitePlus
K134 Ubiquitination PhosphoSitePlus
Y153 Phosphorylation PhosphoSitePlus
K162 Acetylation PhosphoSitePlus
S165 Phosphorylation PhosphoSitePlus
Y167 Phosphorylation PhosphoSitePlus
K169 Acetylation PhosphoSitePlus
T204 Phosphorylation PhosphoSitePlus
Y206 Phosphorylation PhosphoSitePlus
T215 Phosphorylation PhosphoSitePlus
T235 Phosphorylation HPRD 20068231
Y250 Phosphorylation PhosphoSitePlus
Y293 Phosphorylation PhosphoSitePlus
K311 Ubiquitination PhosphoSitePlus
K317 Ubiquitination PhosphoSitePlus
S321 Phosphorylation PhosphoSitePlus
S329 Phosphorylation PhosphoSitePlus
S360 Phosphorylation PhosphoSitePlus
K365 Ubiquitination PhosphoSitePlus
K407 Ubiquitination PhosphoSitePlus
T416 Phosphorylation PhosphoSitePlus
Y417 Phosphorylation PhosphoSitePlus
Y438 Phosphorylation PhosphoSitePlus
S449 Phosphorylation PhosphoSitePlus
S450 Phosphorylation PhosphoSitePlus
S451 Phosphorylation PhosphoSitePlus
S452 Phosphorylation PhosphoSitePlus
K460 Methylation PhosphoSitePlus
S463 Phosphorylation PhosphoSitePlus
S464 Phosphorylation PhosphoSitePlus
S468 Phosphorylation PhosphoSitePlus
S472 Phosphorylation PhosphoSitePlus
S473 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S10 F10 Biomuta DOID:1319 / brain cancer [ cosmic ]
S13 F13 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S17 F17 Biomuta DOID:4159 / skin cancer [ cosmic ]
S28 Y28 Biomuta DOID:263 / kidney cancer [ cosmic ]
S39 F39 Biomuta DOID:4159 / skin cancer [ cosmic, icgc, tcga ]
Y46 H46 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S51 F51 Biomuta DOID:4159 / skin cancer [ cosmic, icgc, tcga ]
S165 I165 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
S165 N165 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
Y167 * Biomuta DOID:3571 / liver cancer [ cosmic ]
K169 N169 Biomuta DOID:363 / uterine cancer [ icgc ]
T215 S215 Biomuta DOID:10534 / stomach cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
S321 A321 Biomuta DOID:4159 / skin cancer [ cosmic ]
S450 P450 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S451 L451 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K460 M460 Biomuta DOID:3571 / liver cancer [ cosmic ]
S464 L464 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ] DOID:3571 / liver cancer [ cosmic ]
S468 I468 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S472 R472 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]