iPTMnet Report for P08572 (COL4A2)
Protein Information
UniProt AC / UniProt ID | P08572 / CO4A2_HUMAN |
Protein Name | Collagen alpha-2(IV) chain precursor |
Gene Name | Name: COL4A2 |
Organism | Homo sapiens (Human) |
PRO ID | PR:P08572 |
PRO Name | collagen alpha-2(IV) chain (human) |
Definition | A collagen alpha-2(IV) chain that is encoded in the genome of human. |
Short Label | hCOL4A2 |
Category | organism-gene |
P08572 (COL4A2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S111 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
N138 | N-Glycosylation | score3 | GlyGen UniProt | 3198637 | ||
T265 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
Y306 | Phosphorylation | score1 | PhosphoSitePlus | |||
S321 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y327 | Phosphorylation | score1 | PhosphoSitePlus | |||
K453 | Acetylation | score1 | PhosphoSitePlus | |||
K456 | Acetylation | score1 | PhosphoSitePlus | |||
K1002 | Acetylation | score1 | PhosphoSitePlus | |||
T1087 | O-Glycosylation | score1 | GlyGen | 34846842 | ||
T1096 | O-Glycosylation | score1 | GlyGen | 34846842 | ||
T1204 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1303 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1309 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1313 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1361 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
T1403 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
T1403 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
S1446 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
S1446 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1485 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1494 | Acetylation | score1 | PhosphoSitePlus | |||
Y1586 | Phosphorylation | score0 | HPRD | 20068231 | ||
S1683 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1687 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
Y327 | * | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
K453 | E453 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] | |
K456 | N456 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
T1204 | I1204 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S1687 | L1687 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ] |