iPTMnet Report for P08096 (top2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P08096 / TOP2_SCHPO
Protein Name DNA topoisomerase 2
Gene Name Name: top2
ORFNames:SPBC1A4.03c;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)

PRO ID PR:P08096
DAG View
PRO Name DNA topoisomerase 2 (Schizosaccharomyces pombe 972h-)
Definition A protein that is a translation product of the top2 gene in Schizosaccharomyces pombe 972h-.
Short Label Spom972h-top2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P08096 (top2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation PomBase 29996109
S8 Phosphorylation PomBase 21712547, 33823663, 29996109
Y10 Phosphorylation PomBase 33823663
S15 Phosphorylation PomBase 21712547, 24763107, 29996109, ...33823663
K29 Sumoylation PomBase 28552615
S43 Phosphorylation PomBase 29996109
T44 Phosphorylation PomBase 27984725, 29996109, 30726745
K246 Ubiquitination PomBase 37970674
K388 Sumoylation PomBase 26537787
K449 Sumoylation PomBase 26537787
K449 Ubiquitination PomBase 37970674
K463 Sumoylation PomBase 26537787
K463 Ubiquitination PomBase 37970674
K470 Ubiquitination PomBase 37970674
K484 Ubiquitination PomBase 37970674
K494 Ubiquitination PomBase 37970674
K533 Ubiquitination PomBase 37970674
K549 Ubiquitination PomBase 37970674
K570 Ubiquitination PomBase 37970674
K656 Sumoylation PomBase 26537787
K697 Sumoylation PomBase 26537787, 28552615
K697 Ubiquitination PomBase 37970674
K704 Sumoylation PomBase 28552615
K753 Sumoylation PomBase 28552615
K753 Ubiquitination PomBase 37970674
K773 Sumoylation PomBase 26537787, 28552615
K773 Ubiquitination PomBase 37970674
K931 Ubiquitination PomBase 37970674
K950 Sumoylation PomBase 26537787
K978 Sumoylation PomBase 26537787
K1017 Sumoylation PomBase 26537787
K1170 Ubiquitination PomBase 37970674
K1184 Sumoylation PomBase 26537787
K1228 Sumoylation PomBase 26537787
K1234 Sumoylation PomBase 28552615
K1254 Sumoylation PomBase 26537787, 28552615
K1254 Ubiquitination PomBase 37970674
K1255 Sumoylation PomBase 26537787
K1262 Sumoylation PomBase 28552615
K1269 Sumoylation PomBase 26537787, 28552615
K1280 Sumoylation PomBase 26537787
K1280 Ubiquitination PomBase 37970674
K1284 Sumoylation PomBase 26537787
K1292 Sumoylation PomBase 26537787, 28552615
S1308 Phosphorylation PomBase 30726745, 21712547, 25720772
K1309 Sumoylation PomBase 26537787
S1310 Phosphorylation PomBase   UniProt 18257517, 24763107, 33823663, ...29996109, 30635402, 21712547, 25720772, 30726745
S1315 Phosphorylation PomBase 30726745, 29996109, 25720772
S1316 Phosphorylation PomBase 30726745, 25720772
K1320 Ubiquitination PomBase 37970674
S1325 Phosphorylation PomBase 21712547, 29996109
S1327 Phosphorylation PomBase 24763107, 33823663, 29996109, ...30726745, 21712547, 25720772
S1330 Phosphorylation PomBase 24763107, 33823663, 29996109, ...30726745, 21712547, 25720772
S1335 Phosphorylation PomBase 30726745, 21712547
K1336 Sumoylation PomBase 28552615
K1337 Sumoylation PomBase 28552615
K1340 Sumoylation PomBase 28552615
K1341 Sumoylation PomBase 28552615
S1345 Phosphorylation UniProt 18257517
T1359 Phosphorylation PomBase 29996109, 25720772
T1360 Phosphorylation PomBase 29996109, 25720772
S1363 Phosphorylation PomBase 24763107, 33823663, 29996109, ...30635402, 21712547, 25720772, 30726745
S1364 Phosphorylation PomBase 18257517, 24763107, 33823663, ...29996109, 30635402, 21712547, 25720772, 30726745
K1376 Sumoylation PomBase 26537787
K1398 Sumoylation PomBase 26537787, 28552615
K1399 Sumoylation PomBase 26537787
S1401 Phosphorylation PomBase 18257517, 27984725, 21712547, ...25720772, 33823663
S1414 Phosphorylation PomBase 29996109
S1415 Phosphorylation PomBase 21712547, 25720772
S1416 Phosphorylation PomBase 29996109, 30635402
T1417 Phosphorylation PomBase 27984725, 29996109, 25720772, ...30635402
S1421 Phosphorylation PomBase 29996109
S1422 Phosphorylation PomBase 33823663, 29996109, 25720772
T1423 Phosphorylation PomBase 29996109, 25720772
S1431 Phosphorylation PomBase 21712547, 33823663, 29996109, ...25720772, 30635402
S1433 Phosphorylation PomBase   UniProt 18257517, 30726745, 33823663, ...29996109, 30635402, 21712547, 25720772
K1437 Sumoylation PomBase 26537787, 28552615