Protein Information

Cytoscape View


UniProt AC / UniProt ID P07947 / YES_HUMAN
Protein Name Tyrosine-protein kinase Yes
Gene Name Name: YES1
Synonyms:YES;
Organism Homo sapiens (Human)

PRO ID PR:P07947
DAG View
PRO Name tyrosine-protein kinase Yes (human)
Definition A tyrosine-protein kinase Yes that is encoded in the genome of human.
Short Label hYES1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P07947 (YES1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S11 Phosphorylation HPRD   PhosphoSitePlus 18691976
K15 Ubiquitination PhosphoSitePlus
Y16 Phosphorylation PhosphoSitePlus
T21 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18691976, 18669648
S26 Phosphorylation HPRD   PhosphoSitePlus 18691976
T27 Phosphorylation HPRD 18691976
S28 Phosphorylation HPRD   PhosphoSitePlus 18691976
S30 Phosphorylation HPRD   PhosphoSitePlus 18691976
Y32 Phosphorylation HPRD   neXtProt   phospho.ELM   PhosphoSitePlus 18083107, 9058199
Y32 Phosphorylation P07947 (YES1) neXtProt 9058199
T37 Phosphorylation PhosphoSitePlus
T38 Phosphorylation PhosphoSitePlus
S40 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18691976, 18669648
S44 Phosphorylation HPRD   phospho.ELM 18669648
S45 Phosphorylation HPRD   PhosphoSitePlus 18669648
S46 Phosphorylation PhosphoSitePlus
Y100 Phosphorylation PhosphoSitePlus
S111 Phosphorylation HPRD   PhosphoSitePlus 18691976
K138 Ubiquitination PhosphoSitePlus
Y141 Phosphorylation PhosphoSitePlus
S144 Phosphorylation PhosphoSitePlus
Y146 Phosphorylation PhosphoSitePlus
Y159 Phosphorylation PhosphoSitePlus
S187 Phosphorylation PhosphoSitePlus
T190 Phosphorylation PhosphoSitePlus
K191 Ubiquitination PhosphoSitePlus
Y194 Phosphorylation HPRD   PhosphoSitePlus 18669648
S195 Phosphorylation HPRD   PhosphoSitePlus 18691976
S197 Phosphorylation PhosphoSitePlus
Y222 Phosphorylation phospho.ELM   PhosphoSitePlus 18083107
Y223 Phosphorylation phospho.ELM   PhosphoSitePlus 18083107
T226 Phosphorylation PhosphoSitePlus
K235 Ubiquitination PhosphoSitePlus
K238 Ubiquitination PhosphoSitePlus
K250 Ubiquitination PhosphoSitePlus
K259 Ubiquitination PhosphoSitePlus
T262 Phosphorylation PhosphoSitePlus
K267 Ubiquitination PhosphoSitePlus
S276 Phosphorylation PhosphoSitePlus
K325 Ubiquitination PhosphoSitePlus
Y336 Phosphorylation PhosphoSitePlus   UniProt 19369195
Y345 Phosphorylation PhosphoSitePlus   UniProt 19369195
S355 Phosphorylation PhosphoSitePlus
K361 Ubiquitination PhosphoSitePlus
Y426 Phosphorylation HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   Signor   UniProt 19651622, 9058199, 17081983, ...16094384, 9794236, 17192257, 18083107, 18691976, 18669648, 18707149
Y426 Phosphorylation P07947 (YES1) HPRD   neXtProt   Signor   UniProt 18691976, 9058199, 17081983, ...9794236, 19651622, 18669648, 18707149
T427 Phosphorylation PhosphoSitePlus
K433 Ubiquitination PhosphoSitePlus
K437 Ubiquitination PhosphoSitePlus
Y446 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18083107
K468 Ubiquitination PhosphoSitePlus
Y489 Phosphorylation PhosphoSitePlus
K510 Ubiquitination PhosphoSitePlus
T531 Phosphorylation PhosphoSitePlus
T533 Phosphorylation PhosphoSitePlus
Y537 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19369195, 18691976, 7690925, ...16439366, 18083107
Y537 Phosphorylation P41240 (CSK) PhosphoSitePlus 16439366


P07947 (YES1) as PTM Enzyme



Substrate Site Score Source PMID
P07947 (YES1) Y32 neXtProt 9058199
P07947 (YES1) Y426 HPRD   neXtProt   Signor   UniProt 18691976, 9058199, 17081983, ...9794236, 19651622, 18669648, 18707149
P11802 (CDK4) Y17 neXtProt   PhosphoSitePlus   Signor 18479465
P15529-7 (CD46) Y324 HPRD 11901164
P15529-12 (CD46) Y338 HPRD 11901164
P15529-11 (CD46) Y353 HPRD 11901164
P15529-4 (CD46) Y354 neXtProt 11901164
P15529-1 (CD46) Y368 HPRD 11901164
P46527 (CDKN1B) Y74 HPRD   neXtProt   PhosphoSitePlus 17254967
P46527 (CDKN1B) Y88 HPRD   neXtProt   PhosphoSitePlus 17254967
P46527 (CDKN1B) Y89 neXtProt   PhosphoSitePlus 17254967
Q05397 (PTK2) Y576 neXtProt 16293639
Q05397 (PTK2) Y861 PhosphoSitePlus 25868388
Q05397 (PTK2) Y925 PhosphoSitePlus 25868388
Q05655 (PRKCD) Y313 neXtProt 18387943
Q05655 (PRKCD) Y334 neXtProt 18387943
Q16543 (CDC37) Y298 PhosphoSitePlus 22727666
Q16555 (DPYSL2) Y479 PhosphoSitePlus 19276087
Q8TEW0 (PARD3) Y1127 neXtProt 17053785
Q969T9 (WBP2) Y192 PhosphoSitePlus   Signor 21642474
Q969T9 (WBP2) Y231 PhosphoSitePlus   Signor 21642474