Protein Information

Cytoscape View


UniProt AC / UniProt ID P07476 / INVO_HUMAN
Protein Name Involucrin
Gene Name Name: IVL
Organism Homo sapiens (Human)

PRO ID PR:P07476
DAG View
PRO Name involucrin (human)
Definition An involucrin that is encoded in the genome of human.
Short Label hIVL
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P07476 (IVL) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S12 Phosphorylation PhosphoSitePlus
S16 Phosphorylation PhosphoSitePlus
T65 Phosphorylation PhosphoSitePlus
K314 Acetylation PhosphoSitePlus
T561 O-Glycosylation GlyGen 34105348


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S12 F12 Biomuta [ cosmic ] DOID:4159 / skin cancer [ cosmic ]
S16 I16 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T561 R561 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]