iPTMnet Report for P07202 (TPO)
Protein Information
| UniProt AC / UniProt ID | P07202 / PERT_HUMAN |
| Protein Name | Thyroid peroxidase precursor |
| Gene Name | Name: TPO |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P07202 |
| PRO Name | thyroid peroxidase (human) |
| Definition | A thyroid peroxidase that is encoded in the genome of human. |
| Short Label | hTPO |
| Category | organism-gene |
DAG ViewP07202 (TPO) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T52 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y55 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T57 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S97 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T561 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K879 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T891 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| Y55 | * | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| Y55 | H55 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| T57 | M57 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic, icgc ] DOID:1319 / brain cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| S97 | P97 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| S97 | * | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| T561 | M561 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:1725 / peritoneum cancer [ cosmic ] | |
| T891 | P891 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] |
