iPTMnet Report for P07199 (CENPB)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P07199 / CENPB_HUMAN
Protein Name Major centromere autoantigen B
Gene Name Name: CENPB
Organism Homo sapiens (Human)

PRO ID PR:P07199
DAG View
PRO Name major centromere autoantigen B (human)
Definition A major centromere autoantigen B that is encoded in the genome of human.
Short Label hCENPB
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P07199 (CENPB) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
G2 Methylation UniProt 23978223
S55 Phosphorylation PhosphoSitePlus
K58 Ubiquitination PhosphoSitePlus
Y59 Phosphorylation PhosphoSitePlus
K70 Sumoylation PhosphoSitePlus
K70 Ubiquitination PhosphoSitePlus
K96 Ubiquitination PhosphoSitePlus
T150 Phosphorylation HPRD   PhosphoSitePlus 20068231
S156 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 19664995, 23186163, ...18220336, 19007248, 16565220, 19651622, 20068231, 19691289
S162 Phosphorylation PhosphoSitePlus
S165 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19691289, 20068231, 16565220
S168 Phosphorylation PhosphoSitePlus
T169 Phosphorylation HPRD 20068231
T170 Phosphorylation PhosphoSitePlus
K246 Ubiquitination PhosphoSitePlus
K266 Ubiquitination PhosphoSitePlus
K276 Ubiquitination PhosphoSitePlus
K279 Ubiquitination PhosphoSitePlus
S303 Phosphorylation PhosphoSitePlus
T306 Phosphorylation HPRD 20068231
S307 Phosphorylation HPRD   PhosphoSitePlus 19691289
K334 Ubiquitination PhosphoSitePlus
T396 Phosphorylation PhosphoSitePlus   UniProt 23186163
T398 Phosphorylation HPRD   PhosphoSitePlus   UniProt 20068231
S400 Phosphorylation HPRD   PhosphoSitePlus 20068231
S486 Phosphorylation HPRD 19007248


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K96 E96 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T150 P150 Biomuta DOID:4159 / skin cancer [ cosmic ]
S162 L162 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T169 I169 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S307 T307 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
T396 S396 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S400 F400 Biomuta DOID:1324 / lung cancer [ cosmic ]
S486 N486 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]