iPTMnet Report for P06732 (CKM)
Protein Information
UniProt AC / UniProt ID | P06732 / KCRM_HUMAN |
Protein Name | Creatine kinase M-type |
Gene Name | Name: CKM Synonyms:CKMM; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P06732 |
PRO Name | creatine kinase M-type (human) |
Definition | A creatine kinase M-type that is encoded in the genome of human. |
Short Label | hCKM |
Category | organism-gene |
P06732 (CKM) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
Y14 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y20 | Phosphorylation | score1 | PhosphoSitePlus | |||
S24 | Phosphorylation | score1 | PhosphoSitePlus | |||
T35 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y39 | Phosphorylation | score1 | PhosphoSitePlus | |||
K40 | Acetylation | score1 | PhosphoSitePlus | |||
K41 | Acetylation | score1 | PhosphoSitePlus | |||
Y125 | Phosphorylation | score1 | PhosphoSitePlus | |||
S128 | Phosphorylation | score1 | PhosphoSitePlus | |||
S129 | Phosphorylation | score1 | PhosphoSitePlus | |||
S136 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y140 | Phosphorylation | score1 | PhosphoSitePlus | |||
T141 | Phosphorylation | score1 | PhosphoSitePlus | |||
S164 | Phosphorylation | score1 | PhosphoSitePlus | |||
T166 | Phosphorylation | score1 | PhosphoSitePlus | |||
K170 | Acetylation | score1 | PhosphoSitePlus | |||
Y173 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y174 | Phosphorylation | score1 | PhosphoSitePlus | |||
S178 | Phosphorylation | score1 | PhosphoSitePlus | |||
T180 | Phosphorylation | score1 | PhosphoSitePlus | |||
S199 | Phosphorylation | score1 | PhosphoSitePlus | |||
R215 | Methylation | score1 | PhosphoSitePlus | |||
S224 | Phosphorylation | score1 | PhosphoSitePlus | |||
K247 | Acetylation | score1 | PhosphoSitePlus | |||
K265 | Acetylation | score1 | PhosphoSitePlus | |||
Y279 | Phosphorylation | score1 | PhosphoSitePlus | |||
T313 | Phosphorylation | score1 | PhosphoSitePlus | |||
T322 | Phosphorylation | score1 | PhosphoSitePlus | |||
T327 | Phosphorylation | score1 | PhosphoSitePlus | |||
S332 | Phosphorylation | score1 | PhosphoSitePlus | |||
K365 | Acetylation | score1 | PhosphoSitePlus | |||
S372 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T35 | I35 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
K40 | R40 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
K41 | Q41 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
S136 | R136 | Biomuta | DOID:263 / kidney cancer [ cosmic ] | |
T166 | M166 | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:5158 / pleural cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] | |
T166 | A166 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
T180 | M180 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] |