Protein Information

Cytoscape View


UniProt AC / UniProt ID P06700 / SIR2_YEAST
Protein Name NAD-dependent histone deacetylase SIR2
Gene Name Name: SIR2
Synonyms:MAR1;OrderedLocusNames:YDL042C;ORFNames:D2714;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

PRO ID PR:P06700
DAG View
PRO Name NAD-dependent histone deacetylase SIR2 (yeast)
Definition A protein that is a translation product of the SIR2 gene in yeast.
Short Label ySIR2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P06700 (SIR2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K17 Sumoylation SGD 33502312
S19 Phosphorylation SGD 33481703
S23 Phosphorylation BioGRID   SGD 19795423, 19823750, 17563356, ...17330950, 20489023, 20702584, 18407956, 23749301, 19779198, 32597660, 33491328, 33481703
T25 Phosphorylation BioGRID   SGD 19823750, 19795423, 33481703, ...33491328
K50 Sumoylation SGD 33502312
K82 Sumoylation SGD 33502312
T109 Phosphorylation BioGRID 20489023
S192 Phosphorylation SGD 33491328
S204 Phosphorylation SGD 33481703
Y400 Phosphorylation BioGRID   SGD 18407956
S420 Phosphorylation SGD 33491328
T561 Phosphorylation SGD 33491328