iPTMnet Report for P06576 (ATP5F1B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P06576 / ATPB_HUMAN
Protein Name ATP synthase subunit beta, mitochondrial precursor
Gene Name Name: ATP5F1B
Synonyms:ATP5B;
Organism Homo sapiens (Human)

PRO ID PR:P06576
DAG View
PRO Name ATP synthase subunit beta, mitochondrial (human)
Definition An ATP synthase subunit beta, mitochondrial that is encoded in the genome of human.
Short Label hATP5F1B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P06576 (ATP5F1B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T21 Phosphorylation HPRD   PhosphoSitePlus 20068231
S23 Phosphorylation HPRD   PhosphoSitePlus 20068231
S25 Phosphorylation HPRD   PhosphoSitePlus 20068231
S51 Phosphorylation PhosphoSitePlus
K55 Methylation PhosphoSitePlus
K55 Ubiquitination PhosphoSitePlus
T60 Phosphorylation PhosphoSitePlus
R109 Methylation PhosphoSitePlus
K124 Acetylation PhosphoSitePlus
K124 Ubiquitination PhosphoSitePlus
S128 Phosphorylation HPRD   PhosphoSitePlus 20068231
K133 Acetylation PhosphoSitePlus   UniProt 19608861
K133 Ubiquitination PhosphoSitePlus
T140 Phosphorylation PhosphoSitePlus
R155 Methylation PhosphoSitePlus
K159 Acetylation PhosphoSitePlus
K159 Ubiquitination PhosphoSitePlus
T185 Phosphorylation PhosphoSitePlus
Y196 Phosphorylation PhosphoSitePlus
K198 Acetylation PhosphoSitePlus   UniProt 19608861
K198 Ubiquitination PhosphoSitePlus
K201 Ubiquitination PhosphoSitePlus
T213 Phosphorylation PhosphoSitePlus
Y230 Phosphorylation PhosphoSitePlus
S231 Phosphorylation PhosphoSitePlus
T240 Phosphorylation HPRD   PhosphoSitePlus 20068231
Y247 Phosphorylation PhosphoSitePlus
K259 Acetylation PhosphoSitePlus
K259 Ubiquitination PhosphoSitePlus
K264 Ubiquitination PhosphoSitePlus
Y269 Phosphorylation PhosphoSitePlus
T288 Phosphorylation PhosphoSitePlus
Y292 Phosphorylation PhosphoSitePlus
T312 Phosphorylation PhosphoSitePlus
S316 Phosphorylation PhosphoSitePlus
S319 Phosphorylation PhosphoSitePlus
S327 O-Glycosylation GlyGen 23271734, 33214551, 30397120, ...26374642, 34725712, 30444036, 29351928, 34019948, 35083852, 32119511
S327 Phosphorylation PhosphoSitePlus
T334 Phosphorylation PhosphoSitePlus
K350 Acetylation PhosphoSitePlus
K351 Ubiquitination PhosphoSitePlus
Y361 Phosphorylation PhosphoSitePlus
T374 Phosphorylation PhosphoSitePlus
Y395 Phosphorylation PhosphoSitePlus
S403 Phosphorylation PhosphoSitePlus
S415 Phosphorylation PhosphoSitePlus   UniProt 23186163, 24275569
Y418 Phosphorylation PhosphoSitePlus
K426 Acetylation PhosphoSitePlus   UniProt 19608861
K426 Ubiquitination PhosphoSitePlus
K432 Methylation PhosphoSitePlus
S433 Phosphorylation PhosphoSitePlus
S447 Phosphorylation PhosphoSitePlus
S465 Phosphorylation PhosphoSitePlus
T475 Phosphorylation PhosphoSitePlus
K480 Acetylation PhosphoSitePlus
K480 Ubiquitination PhosphoSitePlus
K485 Acetylation PhosphoSitePlus
K485 Ubiquitination PhosphoSitePlus
K489 Ubiquitination PhosphoSitePlus
Y499 Phosphorylation PhosphoSitePlus
K519 Ubiquitination PhosphoSitePlus
K522 Acetylation PhosphoSitePlus
K522 Ubiquitination PhosphoSitePlus
S528 Phosphorylation HPRD   PhosphoSitePlus 20166139
S529 Phosphorylation HPRD   PhosphoSitePlus   UniProt 20068231, 24275569


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S25 L25 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic, icgc ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
R155 T155 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
R155 K155 Biomuta DOID:3571 / liver cancer [ cosmic ]
T185 I185 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y196 C196 Biomuta DOID:363 / uterine cancer [ cosmic ]
K201 N201 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T213 I213 Biomuta [ cosmic ]
Y230 C230 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y247 C247 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K351 N351 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S403 Y403 Biomuta DOID:1324 / lung cancer [ cosmic ]
K426 Q426 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K426 N426 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
K432 R432 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S433 F433 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
K480 N480 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
K485 M485 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K489 R489 Biomuta DOID:4606 / bile duct cancer [ cosmic ]