iPTMnet Report for P06401 (PGR)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P06401 / PRGR_HUMAN
Protein Name Progesterone receptor
Gene Name Name: PGR
Synonyms:NR3C3;
Organism Homo sapiens (Human)

PRO ID PR:P06401
DAG View
PRO Name progesterone receptor (human)
Definition A progesterone receptor that is encoded in the genome of human.
Short Label hPGR
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P06401 (PGR) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K7 Sumoylation PhosphoSitePlus
S20 Phosphorylation P24941 (CDK2) phospho.ELM   PhosphoSitePlus   Signor   UniProt 11110801
S25 Phosphorylation P24941 (CDK2) neXtProt   PhosphoSitePlus   RLIMS-P   Signor 19706513, 9171245, 11110801
S79 Phosphorylation PhosphoSitePlus
S81 Phosphorylation P68400 (CSNK2A1) phospho.ELM   PhosphoSitePlus   UniProt 21518957, 8702648, 7476977, ...7983041
Y87 Phosphorylation PhosphoSitePlus   RLIMS-P 33841333
S88 Phosphorylation PhosphoSitePlus
S101 Phosphorylation PhosphoSitePlus
S102 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 8702648, 11110801
S130 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 11110801
S162 Phosphorylation P24941 (CDK2) neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 23186163, 32686665, 7476977, ...8702648, 15798179, 9171245, 11110801, 19706513, 18088087
K183 Acetylation PhosphoSitePlus
K183 Ubiquitination PhosphoSitePlus
S190 Phosphorylation P24941 (CDK2) neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 27852068, 15798179, 9171245, ...11110801, 19706513, 10628747
S213 Phosphorylation P24941 (CDK2) neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 19706513, 9171245, 11110801
S227 Phosphorylation PhosphoSitePlus
S294 Phosphorylation P24941 (CDK2) , P28482 (MAPK1) , P27361 (MAPK3) neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 29237804, 23380370, 28412963, ...10655479, 10628747, 17173941, 32563156, 33449351, 12529413, 9171245, 11110801, 19706513, 24853881, 17717077, 8702648, 22593082, 22093824, 27852068, 18202149, 15798179, 12943699
S328 Phosphorylation PhosphoSitePlus
S345 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 24853881, 7476977, 27852068, ...21138753, 32429997, 8702648, 11110801, 18202149
K388 Sumoylation PhosphoSitePlus
K388 Ubiquitination PhosphoSitePlus   UniProt 17347654
S397 Phosphorylation PhosphoSitePlus
S400 Phosphorylation P24941 (CDK2) neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 15572662, 34168461, 18202149, ...9171245, 11110801, 19706513, 33916643
T430 Phosphorylation P24941 (CDK2) neXtProt   RLIMS-P   Signor 19706513, 9171245, 11110801
K464 Methylation PhosphoSitePlus
Y512 Phosphorylation IEDB 35494241
K531 Sumoylation PhosphoSitePlus
S549 Phosphorylation PhosphoSitePlus
S552 Phosphorylation PhosphoSitePlus
S554 Phosphorylation P24941 (CDK2) neXtProt   PhosphoSitePlus   RLIMS-P   Signor 19706513, 9171245, 11110801
S558 Phosphorylation PhosphoSitePlus
S561 Phosphorylation PhosphoSitePlus
R637 Methylation PhosphoSitePlus
S666 Phosphorylation PhosphoSitePlus
S676 Phosphorylation P24941 (CDK2) neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 19706513, 9171245, 11110801
S735 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S81 Phosphorylation P68400 (CSNK2A1) HPRD 7983041
S162 Phosphorylation HPRD 18088087
Site PTM Type PTM Enzyme Score Source PMID
S26 Phosphorylation neXtProt   PhosphoSitePlus 9171245, 11110801
S49 Phosphorylation neXtProt 9171245, 11110801
S63 Phosphorylation PhosphoSitePlus
S112 Phosphorylation PhosphoSitePlus
S130 Phosphorylation PhosphoSitePlus
S164 Phosphorylation PhosphoSitePlus
S236 Phosphorylation PhosphoSitePlus
T266 Phosphorylation neXtProt 9171245, 11110801
S390 Phosphorylation P49841 (GSK3B) neXtProt   PhosphoSitePlus 23880761, 9171245, 11110801
S394 Phosphorylation PhosphoSitePlus
S512 Phosphorylation neXtProt   PhosphoSitePlus 9171245, 11110801


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P06401 (PGR) S400 Q8WYK2 (JDP2) unknown eFIP 20008003