iPTMnet Report for P06280 (GLA)
Protein Information
UniProt AC / UniProt ID | P06280 / AGAL_HUMAN |
Protein Name | Alpha-galactosidase A precursor |
Gene Name | Name: GLA |
Organism | Homo sapiens (Human) |
PRO ID | PR:P06280 |
PRO Name | alpha-galactosidase A (human) |
Definition | An alpha-galactosidase A that is encoded in the genome of human. |
Short Label | hGLA |
Category | organism-gene |
P06280 (GLA) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S23 | Phosphorylation | score1 | PhosphoSitePlus | |||
K127 | Ubiquitination | score1 | PhosphoSitePlus | |||
N139 | N-Glycosylation | score4 | GlyGen UniProt | 15003450, 23090970, 24190977, ... | ||
N192 | N-Glycosylation | score4 | GlyGen UniProt | 15003450, 23090970, 24190977, ... | ||
N215 | N-Glycosylation | score4 | GlyGen UniProt | 15003450, 29741879, 19159218, ... | ||
K237 | Ubiquitination | score1 | PhosphoSitePlus | |||
K240 | Ubiquitination | score1 | PhosphoSitePlus | |||
K308 | Ubiquitination | score1 | PhosphoSitePlus | |||
K314 | Ubiquitination | score1 | PhosphoSitePlus | |||
K326 | Ubiquitination | score1 | PhosphoSitePlus | |||
S371 | Phosphorylation | score2 | IEDB PhosphoSitePlus | 35494241 | ||
K391 | Ubiquitination | score1 | PhosphoSitePlus | |||
K393 | Ubiquitination | score1 | PhosphoSitePlus | |||
R402 | Methylation | score1 | PhosphoSitePlus | |||
S424 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K308 | R308 | Biomuta | DOID:184 / bone cancer [ cosmic ] | |
R402 | M402 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] |