iPTMnet Report for P06169 (PDC1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P06169 / PDC1_YEAST
Protein Name Pyruvate decarboxylase isozyme 1
Gene Name Name: PDC1
OrderedLocusNames:YLR044C;ORFNames:L2104;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

PRO ID PR:P06169
DAG View
PRO Name pyruvate decarboxylase isozyme 1 (yeast)
Definition A protein that is a translation product of the PDC1 gene in yeast.
Short Label yPDC1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P06169 (PDC1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 10545125, 9298649
S2 Phosphorylation BioGRID 19795423, 19823750
K8 Acetylation SGD 22865919
Y38 Phosphorylation SGD 33481703
Y56 Phosphorylation SGD 33481703
T155 Phosphorylation SGD 33481703
R161 Methylation SGD   UniProt 26046779
Y164 Phosphorylation SGD 33481703
T183 Phosphorylation SGD 33481703, 33491328
S188 Phosphorylation SGD 33481703
K190 Acetylation SGD 22865919
K190 Ubiquitination SGD 25344756, 23749301
S196 Phosphorylation BioGRID   SGD 19823750, 19795423, 33481703, ...33491328
K198 Ubiquitination SGD 23749301
T203 Phosphorylation BioGRID 19795423, 19823750
K209 Acetylation SGD 22865919
K209 Sumoylation SGD 33502312
K212 Sumoylation SGD 33502312
K212 Ubiquitination SGD   UniProt 22106047, 25344756, 23749301
S223 Phosphorylation BioGRID   SGD   UniProt 19795423, 33481703, 17330950, ...18407956, 33491328, 19779198, 11283598, 19684113, 32597660, 23749301, 19823750
K228 Acetylation SGD 22865919
K228 Sumoylation SGD 33502312
K232 Sumoylation SGD 33502312
K233 Acetylation SGD 22865919
K233 Sumoylation SGD 33502312
K233 Ubiquitination SGD   UniProt 30489083, 22106047, 25344756, ...23749301
T238 Phosphorylation BioGRID 21126336
T245 Phosphorylation SGD 33481703, 33491328
K249 Ubiquitination SGD 23749301
S251 Phosphorylation SGD 32597660, 33481703, 33491328
Y259 Phosphorylation SGD 33481703
Y263 Phosphorylation SGD 33481703
T266 Phosphorylation BioGRID   SGD   UniProt 33481703, 33491328, 18407956, ...23749301
S268 Phosphorylation SGD 33481703, 33491328, 23749301
K269 Acetylation SGD 22865919
K269 Ubiquitination SGD   UniProt 22106047, 23749301
K304 Acetylation SGD 22865919
K304 Sumoylation SGD 33502312
K304 Ubiquitination SGD 23749301
S311 Phosphorylation SGD 33481703, 33491328
K315 Acetylation SGD 22865919
K315 Ubiquitination SGD 23749301
T320 Phosphorylation BioGRID   SGD 33481703, 18407956
K327 Acetylation SGD 22865919
K332 Acetylation SGD 22865919
K332 Ubiquitination SGD   UniProt 22106047, 23749301
T335 Phosphorylation BioGRID   SGD 19779198, 33481703, 33491328, ...21126336, 23749301
T336 Phosphorylation BioGRID   SGD   UniProt 19779198, 33481703, 33491328, ...23749301
K342 Acetylation SGD 22865919
K342 Ubiquitination SGD 23749301
Y344 Phosphorylation SGD 33481703
K345 Acetylation SGD 22865919
K345 Ubiquitination SGD 30489083, 23749301
T353 Phosphorylation BioGRID   SGD   UniProt 33481703, 17330950, 21126336, ...23749301, 19779198, 32597660, 33491328
S362 Phosphorylation BioGRID   SGD 19779198, 33481703, 18407956, ...33491328
T363 Phosphorylation BioGRID   SGD 33481703, 18407956, 33491328
K484 Sumoylation SGD 33502312
K484 Ubiquitination SGD   UniProt 22106047, 23749301
S497 Phosphorylation SGD 33481703, 33491328
K505 Ubiquitination SGD   UniProt 22106047, 23749301
T509 Phosphorylation BioGRID 17287358
T514 Phosphorylation BioGRID   SGD 33491328, 33481703, 17287358
T515 Phosphorylation BioGRID   SGD 19779198, 33481703, 33491328, ...23749301
K520 Acetylation SGD 22865919
K520 Sumoylation SGD 33502312
K520 Ubiquitination SGD   UniProt 30489083, 22106047, 25344756, ...23749301
T522 Phosphorylation BioGRID   SGD   UniProt 19779198, 33481703, 33491328
K525 Acetylation SGD 22865919
K525 Sumoylation SGD 33502312
K525 Ubiquitination SGD 30489083, 23749301
S526 Phosphorylation BioGRID   SGD   UniProt 33481703, 18407956, 23749301, ...19779198, 32597660, 33491328
S531 Phosphorylation SGD 32597660, 23749301, 33491328
K532 Acetylation SGD 22865919
K532 Ubiquitination SGD 23749301
K554 Sumoylation SGD 33502312
K562 Sumoylation SGD 33502312
K562 Ubiquitination SGD 23749301