iPTMnet Report for P06132 (UROD)
Protein Information
| UniProt AC / UniProt ID | P06132 / DCUP_HUMAN |
| Protein Name | Uroporphyrinogen decarboxylase |
| Gene Name | Name: UROD |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P06132 |
| PRO Name | uroporphyrinogen decarboxylase (human) |
| Definition | A uroporphyrinogen decarboxylase that is encoded in the genome of human. |
| Short Label | hUROD |
| Category | organism-gene |
DAG ViewP06132 (UROD) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| M1 | Acetylation | score1 | UniProt | 19413330, 22814378, 22223895 | ||
| K15 | Acetylation | score1 | PhosphoSitePlus | |||
| K15 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y30 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S61 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y133 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T139 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T141 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K289 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K290 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C294 | Methylation | score1 | IEDB | 31844290 | ||
| K297 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y342 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K359 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S61 | F61 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |
