iPTMnet Report for P05981 (HPN)
Protein Information
UniProt AC / UniProt ID | P05981 / HEPS_HUMAN |
Protein Name | Serine protease hepsin |
Gene Name | Name: HPN Synonyms:TMPRSS1; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P05981 |
PRO Name | serine protease hepsin (human) |
Definition | A serine protease hepsin that is encoded in the genome of human. |
Short Label | hHPN |
Category | organism-gene |
P05981 (HPN) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
N112 | N-Glycosylation | score2 | GlyGen UniProt | 19159218 | ||
Y341 | Phosphorylation | score1 | PhosphoSitePlus | |||
S353 | Phosphorylation | score1 | PhosphoSitePlus | |||
S362 | Phosphorylation | score1 | PhosphoSitePlus | |||
S364 | Phosphorylation | score1 | PhosphoSitePlus | |||
K386 | Ubiquitination | score1 | PhosphoSitePlus | |||
K392 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S362 | G362 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
S364 | C364 | Biomuta | DOID:2394 / ovarian cancer [ icgc ] |