iPTMnet Report for P05546 (SERPIND1)
Protein Information
UniProt AC / UniProt ID | P05546 / HEP2_HUMAN |
Protein Name | Heparin cofactor 2 precursor |
Gene Name | Name: SERPIND1 Synonyms:HCF2; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P05546 |
PRO Name | heparin cofactor 2 (human) |
Definition | A heparin cofactor 2 that is encoded in the genome of human. |
Short Label | hSERPIND1 |
Category | organism-gene |
P05546 (SERPIND1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S37 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
S37 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 19824718, 26091039 | ||
N49 | N-Glycosylation | score2 | GlyGen UniProt | 16335952, 32125861, 19159218, ... | ||
S51 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
T66 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y79 | Phosphorylation | score1 | PhosphoSitePlus | |||
S100 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
S102 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
T104 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
Y138 | Phosphorylation | score1 | PhosphoSitePlus | |||
N188 | N-Glycosylation | score4 | GlyGen UniProt | 16335952, 19159218, 29391424, ... | ||
T328 | O-Glycosylation | score1 | GlyGen | 31492838 | ||
N387 | N-Glycosylation | score3 | GlyGen UniProt | 12169660 | ||
T453 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
T454 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
T457 | O-Glycosylation | score1 | GlyGen | 30459171 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S102 | C102 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
T104 | R104 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
T457 | M457 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
T457 | A457 | Biomuta | DOID:3571 / liver cancer [ cosmic ] |