iPTMnet Report for P05388 (RPLP0)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P05388 / RLA0_HUMAN
Protein Name Large ribosomal subunit protein uL10
Gene Name Name: RPLP0
Organism Homo sapiens (Human)

PRO ID PR:P05388
DAG View
PRO Name 60S acidic ribosomal protein P0 (human)
Definition A 60S acidic ribosomal protein P0 that is encoded in the genome of human.
Short Label hRPLP0
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P05388 (RPLP0) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R6 Methylation PhosphoSitePlus
T8 Phosphorylation PhosphoSitePlus
K10 Acetylation PhosphoSitePlus
K10 Methylation PhosphoSitePlus
K10 Ubiquitination PhosphoSitePlus
K16 Methylation PhosphoSitePlus
K16 Ubiquitination PhosphoSitePlus
Y24 Phosphorylation phospho.ELM   PhosphoSitePlus 15592455, 18083107
K26 Ubiquitination PhosphoSitePlus
C27 S-Nitrosylation dbSNO 2212679, 22126794, 22178444, ...20140087
S37 Phosphorylation PhosphoSitePlus
K38 Ubiquitination PhosphoSitePlus
K50 Ubiquitination PhosphoSitePlus
K57 Ubiquitination PhosphoSitePlus
T59 Phosphorylation PhosphoSitePlus   UniProt 23186163
R66 Methylation PhosphoSitePlus
K77 Acetylation PhosphoSitePlus
K77 Ubiquitination PhosphoSitePlus
K92 Ubiquitination PhosphoSitePlus
K106 Acetylation PhosphoSitePlus
K106 Ubiquitination PhosphoSitePlus
R112 Methylation PhosphoSitePlus
C119 Methylation IEDB 31844290
C119 S-Nitrosylation dbSNO 2212679, 22178444
T122 O-Glycosylation GlyGen 27114449, 35138101, 30379171, ...34725712, 35254053, 35132862, 35083852, 32119511, 22121020
T122 Phosphorylation PhosphoSitePlus
T128 Phosphorylation PhosphoSitePlus
K134 Ubiquitination PhosphoSitePlus
T135 Phosphorylation PhosphoSitePlus
S136 Phosphorylation PhosphoSitePlus
K146 Ubiquitination PhosphoSitePlus
S148 Phosphorylation PhosphoSitePlus
T151 Phosphorylation PhosphoSitePlus
S156 Phosphorylation PhosphoSitePlus
K162 Ubiquitination PhosphoSitePlus
K166 Ubiquitination PhosphoSitePlus
K246 Acetylation PhosphoSitePlus
K246 Ubiquitination PhosphoSitePlus
S252 Phosphorylation PhosphoSitePlus
Y257 Phosphorylation PhosphoSitePlus
K264 Ubiquitination PhosphoSitePlus   UniProt 36638793
K266 Ubiquitination PhosphoSitePlus
S273 O-Glycosylation GlyGen 27114449, 35138101, 30379171, ...34725712, 35254053, 35132862, 35083852, 32119511, 22121020
S273 Phosphorylation PhosphoSitePlus
T285 Phosphorylation PhosphoSitePlus
T286 O-Glycosylation GlyGen 27114449, 35138101, 30379171, ...34725712, 35254053, 35132862, 35083852, 32119511, 22121020
T286 Phosphorylation PhosphoSitePlus
K297 Sumoylation PhosphoSitePlus
K297 Ubiquitination PhosphoSitePlus
S304 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 14729942, 19369195, 18669648, ...17081983
S307 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 19369195, 17081983, 15302935, ...18669648, 14729942
Site PTM Type PTM Enzyme Score Source PMID
Y24 Phosphorylation HPRD 15592455, 20068231
S273 Phosphorylation HPRD 20068231
T285 Phosphorylation HPRD 20068231
T286 Phosphorylation HPRD 20068231
S304 Phosphorylation HPRD 18691976, 18491316, 20230923, ...19007248, 18452278, 19651622, 17322306, 18669648, 18707149, 20166139, 19415658, 20068231
S307 Phosphorylation HPRD 18691976, 18491316, 20230923, ...18767875, 19007248, 18452278, 19651622, 17322306, 18669648, 18707149, 20166139, 19415658, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y24 N24 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
C27 R27 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T59 A59 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
R112 H112 Biomuta DOID:4159 / skin cancer [ cosmic ]
T122 S122 Biomuta [ cosmic ]
K134 N134 Biomuta DOID:363 / uterine cancer [ icgc ]
S148 F148 Biomuta DOID:4159 / skin cancer [ cosmic ]
S156 R156 Biomuta DOID:4159 / skin cancer [ cosmic ]
K162 N162 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
K166 T166 Biomuta DOID:363 / uterine cancer [ icgc ]
S273 C273 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
S304 L304 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]