iPTMnet Report P05121 SERPINE1

Protein Information

Cytoscape View

UniProt AC / UniProt ID	P05121 / PAI1_HUMAN
Protein Name	Plasminogen activator inhibitor 1 precursor
Gene Name	Name: SERPINE1 Synonyms:PAI1,PLANH1;
Organism	Homo sapiens (Human)

PRO ID	PR:P05121 DAG View
PRO Name	plasminogen activator inhibitor 1 (human)
Definition	A plasminogen activator inhibitor 1 that is encoded in the genome of human.
Short Label	hSERPINE1
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

P05121 (SERPINE1) as Substrate

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	C9	Methylation		score1	IEDB	31844290
	T72	Phosphorylation		score1	IEDB	35494241
	Y102	Phosphorylation		score1	PhosphoSitePlus
	Y193	Phosphorylation		score1	PhosphoSitePlus
	T200	Phosphorylation		score1	PhosphoSitePlus
	N232	N-Glycosylation		score1	GlyGen	23090970, 24190977
	N288	N-Glycosylation		score1	GlyGen	23345538
	S359	O-Glycosylation		score1	GlyGen	30459171
	S360	O-Glycosylation		score1	GlyGen	30459171
	T362	O-Glycosylation		score1	GlyGen	30459171

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	N288	N-Glycosylation		score1	PRO	23345538

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
C9	G9	Biomuta		DOID:363 / uterine cancer [ cosmic, icgc ]
N232	S232	Biomuta		DOID:363 / uterine cancer [ cosmic, icgc ]