iPTMnet Report for P05114 (HMGN1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P05114 / HMGN1_HUMAN
Protein Name Non-histone chromosomal protein HMG-14
Gene Name Name: HMGN1
Synonyms:HMG14;
Organism Homo sapiens (Human)

PRO ID PR:P05114
DAG View
PRO Name non-histone chromosomal protein HMG-14 (human)
Definition A non-histone chromosomal protein HMG-14 that is encoded in the genome of human.
Short Label hHMGN1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P05114 (HMGN1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K3 Acetylation PhosphoSitePlus
K5 Acetylation PhosphoSitePlus
K5 Methylation PhosphoSitePlus
K5 Ubiquitination PhosphoSitePlus
S7 Phosphorylation P68400 (CSNK2A1) , P17612 (PRKACA) , P51812 (RPS6KA3) , O75676 (RPS6KA4) , O75582 (RPS6KA5) , P17252 (PRKCA) HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   Signor 10739259, 20089855, 18669648, ...11438671, 20166139, 12773393, 16729963, 17924679
S8 Phosphorylation P68400 (CSNK2A1) HPRD   phospho.ELM   PhosphoSitePlus   Signor   UniProt 21406692, 10739259, 19664994, ...18669648, 11438671, 16729963, 20068231
K14 Acetylation PhosphoSitePlus   UniProt 19608861
K14 Ubiquitination PhosphoSitePlus
K18 Acetylation PhosphoSitePlus
S21 Phosphorylation P51812 (RPS6KA3) , P17612 (PRKACA) , P17252 (PRKCA) HPRD   phospho.ELM   PhosphoSitePlus   Signor   UniProt 10739259, 11438671, 23186163, ...20068231
S25 Phosphorylation P17612 (PRKACA) , P17252 (PRKCA) , P51812 (RPS6KA3) HPRD   phospho.ELM   PhosphoSitePlus   Signor   UniProt 10739259, 11438671, 23186163, ...20068231
K27 Acetylation PhosphoSitePlus
K27 Ubiquitination PhosphoSitePlus
K31 Acetylation PhosphoSitePlus
K31 Ubiquitination PhosphoSitePlus
K38 Acetylation PhosphoSitePlus
K42 Acetylation PhosphoSitePlus
K48 Acetylation PhosphoSitePlus
K53 Acetylation PhosphoSitePlus
K55 Acetylation PhosphoSitePlus
K59 Acetylation PhosphoSitePlus
K61 Acetylation PhosphoSitePlus
K61 Ubiquitination PhosphoSitePlus
T70 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 15302935
K71 Ubiquitination PhosphoSitePlus
T81 Phosphorylation HPRD   PhosphoSitePlus 20068231
K82 Acetylation PhosphoSitePlus   UniProt 19608861
K82 Ubiquitination PhosphoSitePlus
T83 Phosphorylation HPRD   PhosphoSitePlus 19651622, 20068231
S86 Phosphorylation P68400 (CSNK2A1) HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 21406692, 23186163, ...16729963, 15302935, 18318008, 19651622, 18669648, 24275569, 18452278, 19690332, 20068231
S89 Phosphorylation P68400 (CSNK2A1) HPRD   PhosphoSitePlus   Signor   UniProt 19413330, 21406692, 23186163, ...16729963, 3427111, 10739259, 15302935, 18452278, 19651622, 18669648, 24275569, 18318008, 19690332, 20068231
K95 Ubiquitination PhosphoSitePlus
K98 Ubiquitination PhosphoSitePlus
S99 Phosphorylation P68400 (CSNK2A1) HPRD   phospho.ELM   PhosphoSitePlus   Signor   UniProt 10739259, 15147216, 18452278, ...18669648, 16729963


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S8 P8 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S21 W21 Biomuta DOID:184 / bone cancer [ cosmic ]
S21 L21 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K31 N31 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K42 R42 Biomuta DOID:3571 / liver cancer [ cosmic ]
K55 E55 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
T81 M81 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K82 M82 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K82 R82 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S89 F89 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]