iPTMnet Report for P05089 (ARG1)
Protein Information
UniProt AC / UniProt ID | P05089 / ARGI1_HUMAN |
Protein Name | Arginase-1 |
Gene Name | Name: ARG1 |
Organism | Homo sapiens (Human) |
PRO ID | PR:P05089 |
PRO Name | arginase-1 (human) |
Definition | An arginase-1 that is encoded in the genome of human. |
Short Label | hARG1 |
Category | organism-gene |
P05089 (ARG1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S16 | Phosphorylation | score1 | PhosphoSitePlus | |||
T29 | Phosphorylation | score1 | PhosphoSitePlus | |||
K33 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y50 | Phosphorylation | score1 | PhosphoSitePlus | |||
S62 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
S72 | Phosphorylation | score1 | PhosphoSitePlus | |||
S94 | Phosphorylation | score1 | PhosphoSitePlus | |||
S102 | Phosphorylation | score1 | PhosphoSitePlus | |||
S107 | Phosphorylation | score1 | PhosphoSitePlus | |||
S109 | Phosphorylation | score1 | PhosphoSitePlus | |||
S163 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
T166 | Phosphorylation | score1 | PhosphoSitePlus | |||
C168 | S-Nitrosylation | score2 | dbSNO | 17704205, 22178444 | ||
S170 | Phosphorylation | score1 | PhosphoSitePlus | |||
K191 | Acetylation | score1 | PhosphoSitePlus | |||
S217 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
Y265 | Phosphorylation | score1 | PhosphoSitePlus | |||
C303 | S-Nitrosylation | score2 | dbSNO | 17704205, 22178444 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S16 | * | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S72 | Y72 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ] | |
S94 | R94 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
S109 | P109 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
T166 | I166 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
C168 | R168 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
S170 | P170 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic ] |