iPTMnet Report for P04844 (RPN2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P04844 / RPN2_HUMAN
Protein Name Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 precursor
Gene Name Name: RPN2
Organism Homo sapiens (Human)

PRO ID PR:P04844
DAG View
PRO Name dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 (human)
Definition A dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 that is encoded in the genome of human.
Short Label hRPN2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P04844 (RPN2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K38 Ubiquitination PhosphoSitePlus
S40 Phosphorylation PhosphoSitePlus
T46 Phosphorylation PhosphoSitePlus
S50 Phosphorylation PhosphoSitePlus
S54 O-Glycosylation GlyGen 30397120, 34725712, 29351928, ...34019948, 32119511, 28510447, 33465208
K69 Ubiquitination PhosphoSitePlus
K70 Ubiquitination PhosphoSitePlus
C72 Methylation IEDB 31844290
S77 O-Glycosylation GlyGen 34846842
C100 Methylation IEDB 31844290
N106 N-Glycosylation GlyGen   UniProt 29741879, 19159218, 24190977
K154 Ubiquitination PhosphoSitePlus
T167 Phosphorylation PhosphoSitePlus
S179 Phosphorylation PhosphoSitePlus
Y198 Phosphorylation PhosphoSitePlus
Y216 Phosphorylation PhosphoSitePlus
K229 Ubiquitination PhosphoSitePlus
K243 Ubiquitination PhosphoSitePlus
K244 Ubiquitination PhosphoSitePlus
S257 Phosphorylation PhosphoSitePlus
S280 Phosphorylation PhosphoSitePlus
T282 Phosphorylation PhosphoSitePlus
K306 Sumoylation PhosphoSitePlus
K306 Ubiquitination PhosphoSitePlus
K311 Ubiquitination PhosphoSitePlus
S312 O-Glycosylation GlyGen 30397120, 34725712, 29351928, ...34019948, 32119511, 28510447, 33465208
S315 O-Glycosylation GlyGen 33465208
K322 Ubiquitination PhosphoSitePlus
S324 Phosphorylation PhosphoSitePlus
T326 Phosphorylation PhosphoSitePlus
K368 Ubiquitination PhosphoSitePlus
K385 Ubiquitination PhosphoSitePlus
K392 Ubiquitination PhosphoSitePlus
T397 Phosphorylation PhosphoSitePlus
Y398 Phosphorylation PhosphoSitePlus
K401 Ubiquitination PhosphoSitePlus
T405 Phosphorylation PhosphoSitePlus
K442 Ubiquitination PhosphoSitePlus
K456 Ubiquitination PhosphoSitePlus
K460 Acetylation PhosphoSitePlus
K460 Ubiquitination PhosphoSitePlus
T521 O-Glycosylation GlyGen 25813380
T521 Phosphorylation PhosphoSitePlus
K523 Ubiquitination PhosphoSitePlus
T546 Phosphorylation PhosphoSitePlus
K627 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T157 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
T610 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
C72 Y72 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T167 A167 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S179 I179 Biomuta DOID:363 / uterine cancer [ icgc ]
T405 I405 Biomuta DOID:363 / uterine cancer [ icgc ]
K460 T460 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T521 A521 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]