iPTMnet Report for P04843 (RPN1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P04843 / RPN1_HUMAN
Protein Name Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 precursor
Gene Name Name: RPN1
Organism Homo sapiens (Human)

PRO ID PR:P04843
DAG View
PRO Name dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (human)
Definition A dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 that is encoded in the genome of human.
Short Label hRPN1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P04843 (RPN1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K37 Acetylation PhosphoSitePlus
K37 Ubiquitination PhosphoSitePlus
T39 Phosphorylation PhosphoSitePlus
K48 Ubiquitination PhosphoSitePlus
T50 O-Glycosylation GlyGen 25813380
S62 O-Glycosylation GlyGen 25813380
S64 O-Glycosylation GlyGen 25813380
K89 Ubiquitination PhosphoSitePlus
K116 Ubiquitination PhosphoSitePlus
Y135 Phosphorylation PhosphoSitePlus
T136 Phosphorylation PhosphoSitePlus
T144 O-Glycosylation GlyGen 25813380
Y161 Phosphorylation PhosphoSitePlus
S164 Phosphorylation PhosphoSitePlus
K187 Acetylation PhosphoSitePlus   UniProt 19608861
K187 Ubiquitination PhosphoSitePlus
S194 Phosphorylation PhosphoSitePlus
Y200 Phosphorylation PhosphoSitePlus
Y209 Phosphorylation PhosphoSitePlus
K215 Acetylation PhosphoSitePlus
K215 Ubiquitination PhosphoSitePlus
S222 Phosphorylation PhosphoSitePlus
T228 O-Glycosylation GlyGen 25813380
S237 O-Glycosylation GlyGen 25813380
K258 Ubiquitination PhosphoSitePlus
Y264 Phosphorylation PhosphoSitePlus
Y266 Phosphorylation PhosphoSitePlus
K281 Ubiquitination PhosphoSitePlus
T282 O-Glycosylation GlyGen 23301498, 30444036, 30397120, ...34725712, 33214551, 29351928, 34019948, 35083852, 32870666, 32119511, 35289036, 33465208
Y292 Phosphorylation PhosphoSitePlus
Y293 Phosphorylation PhosphoSitePlus
N299 N-Glycosylation GlyGen   UniProt 29741879, 19159218, 24190977
K327 Acetylation PhosphoSitePlus
K352 Ubiquitination PhosphoSitePlus
S367 O-Glycosylation GlyGen 23301498, 30444036, 30397120, ...34725712, 33214551, 29351928, 34019948, 35083852, 32870666, 32119511, 35289036, 33465208
K371 Ubiquitination PhosphoSitePlus
K379 Ubiquitination PhosphoSitePlus
S385 O-Glycosylation GlyGen 23301498, 30444036, 30397120, ...34725712, 33214551, 29351928, 34019948, 35083852, 32870666, 32119511, 35289036, 33465208
S385 Phosphorylation PhosphoSitePlus
Y387 Phosphorylation PhosphoSitePlus
S390 Phosphorylation PhosphoSitePlus
Y398 Phosphorylation PhosphoSitePlus
T399 Phosphorylation PhosphoSitePlus
K413 Acetylation PhosphoSitePlus
K413 Ubiquitination PhosphoSitePlus
K414 Acetylation PhosphoSitePlus
K414 Ubiquitination PhosphoSitePlus
K465 Ubiquitination PhosphoSitePlus
K474 Ubiquitination PhosphoSitePlus
C477 Methylation IEDB 31844290
C477 S-Nitrosylation dbSNO 19483679, 20140087, 25040305
K488 Ubiquitination PhosphoSitePlus
S510 Phosphorylation HPRD 20068231
S514 Phosphorylation PhosphoSitePlus
K516 Acetylation PhosphoSitePlus
K516 Ubiquitination PhosphoSitePlus
K517 Ubiquitination PhosphoSitePlus
S518 Phosphorylation PhosphoSitePlus
K524 Acetylation PhosphoSitePlus
K524 Ubiquitination PhosphoSitePlus
S528 Phosphorylation PhosphoSitePlus
S535 Phosphorylation PhosphoSitePlus
K538 Acetylation PhosphoSitePlus
K538 Sumoylation PhosphoSitePlus
K538 Ubiquitination PhosphoSitePlus
S542 Phosphorylation PhosphoSitePlus
R547 Methylation PhosphoSitePlus
K553 Acetylation PhosphoSitePlus
K553 Ubiquitination PhosphoSitePlus
K559 Ubiquitination PhosphoSitePlus
K564 Ubiquitination PhosphoSitePlus
K576 Ubiquitination PhosphoSitePlus
K578 Ubiquitination PhosphoSitePlus
K579 Ubiquitination PhosphoSitePlus
K587 Acetylation PhosphoSitePlus
K587 Ubiquitination PhosphoSitePlus
T598 Phosphorylation HPRD   PhosphoSitePlus 20068231
K599 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K89 R89 Biomuta [ cosmic ]
K116 R116 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y135 H135 Biomuta DOID:1612 / breast cancer [ cosmic ]
T144 A144 Biomuta DOID:1319 / brain cancer [ cosmic ]
S222 N222 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S367 Y367 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K371 E371 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S385 N385 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y387 C387 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
Y398 H398 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K474 * Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
K524 T524 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
R547 I547 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K599 N599 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]