iPTMnet Report for P04278 (SHBG)
Protein Information
UniProt AC / UniProt ID | P04278 / SHBG_HUMAN |
Protein Name | Sex hormone-binding globulin precursor |
Gene Name | Name: SHBG |
Organism | Homo sapiens (Human) |
PRO ID | PR:P04278 |
PRO Name | sex hormone-binding globulin (human) |
Definition | A sex hormone-binding globulin that is encoded in the genome of human. |
Short Label | hSHBG |
Category | organism-gene |
P04278 (SHBG) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S3 | Phosphorylation | score1 | PhosphoSitePlus | |||
T36 | O-Glycosylation | score3 | GlyGen | 6684483, 30459171, 1400872, ... | ||
S72 | Phosphorylation | score1 | PhosphoSitePlus | |||
T161 | Phosphorylation | score1 | PhosphoSitePlus | |||
S162 | Phosphorylation | score1 | PhosphoSitePlus | |||
N380 | N-Glycosylation | score4 | GlyGen UniProt | 16335952, 3542030, 19159218, ... | ||
N396 | N-Glycosylation | score4 | GlyGen UniProt | 34725484, 3542030, 23090970, ... |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S3 | N3 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
Y86 | F86 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] |