iPTMnet Report for P04179 (SOD2)
Protein Information
| UniProt AC / UniProt ID | P04179 / SODM_HUMAN |
| Protein Name | Superoxide dismutase [Mn], mitochondrial precursor |
| Gene Name | Name: SOD2 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P04179 |
| PRO Name | superoxide dismutase [Mn], mitochondrial (human) |
| Definition | A superoxide dismutase [Mn], mitochondrial that is encoded in the genome of human. |
| Short Label | hSOD2 |
| Category | organism-gene |
DAG ViewP04179 (SOD2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K53 | Acetylation | score1 | PhosphoSitePlus | |||
| Y58 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K68 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
| T79 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S106 | Phosphorylation | P06493 (CDK1) , P11802 (CDK4) | score4 | PhosphoSitePlus RLIMS-P | 23243068, 25578653 | |
| K122 | Acetylation | score1 | PhosphoSitePlus | |||
| K122 | Methylation | score1 | PhosphoSitePlus | |||
| K122 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S127 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K130 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
| K130 | Methylation | score1 | PhosphoSitePlus | |||
| K130 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K132 | Acetylation | score1 | PhosphoSitePlus | |||
| R197 | Methylation | score1 | PhosphoSitePlus | |||
| K221 | Acetylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S127 | F127 | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ] |
